Recent Research Advances in Nano-Based Drug Delivery Systems for Local Anesthetics

H Ma, Z Pan, B Lai, C Zan, H Liu - Drug Design, Development and …, 2023 - Taylor & Francis
From a clinical perspective, local anesthetics have rather widespread application in regional
blockade for surgery, postoperative analgesia, acute/chronic pain control, and even cancer …

Advances in the use of local anesthetic extended-release systems in pain management

Y Chen, J Xu, P Li, L Shi, S Zhang, Q Guo, Y Yang - Drug Delivery, 2024 - Taylor & Francis
Pain management remains among the most common and largely unmet clinical problems
today. Local anesthetics play an indispensable role in pain management. The main …

Aggregation behaviour of tetracaine hydrochloride with Gemini surfactants and the formation of silver nanoparticles using drug-Gemini surfactants mixture

A Srivastava, U Thapa, M Saha, M Jalees - Journal of Molecular Liquids, 2019 - Elsevier
This study aimed to encapsulate drug into the silver nanoparticles (AgNPs) by using drug-
Gemini surfactant mixed aggregate. The applicability of drug-surfactant based AgNPs is to …

[HTML][HTML] Long-term anesthetic analgesic effects: Comparison of tetracaine loaded polymeric nanoparticles, solid lipid nanoparticles, and nanostructured lipid carriers …

X Liu, Q Zhao - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Local anesthetics (LAs) are drugs that promote the reversible blocking of neural
transmission by inhibiting the excitation conduction process in peripheral nerves. Tetracaine …

New procedure to synthesize silver nanoparticles and their interaction with local anesthetics

A Mocanu, RD Pasca, G Tomoaia, C Garbo… - International Journal …, 2013 - Taylor & Francis
Silver nanoparticles (AgNPs) were prepared in aqueous colloid dispersions by the reduction
of Ag+ with glucose in alkaline medium. Tetraethyl orthosilicate and L-asparagine were …

[PDF][PDF] Silver and gold nanoparticles: challenges and perspectives

MA Ujica, GA Paltinean, A Mocanu… - Acad. Rom. Sci. Ann.-Ser …, 2020 - aos.ro
Syntheses of gold nanoparticles (AuNPs) and silver nanoparticles (AgNPs) were evaluated
with an emphasis on controlling the size, shape and stability of nanoparticles (NPs). Various …

Assessing the Potential for Drug–Nanoparticle Surface Interactions To Improve Drug Penetration into the Skin

XJ Cai, A Woods, P Mesquida… - Molecular …, 2016 - ACS Publications
There is continued debate as to how nanomaterials enhance the passive diffusion of drugs
through the skin. This study examined if drug–nanoparticle surface interactions, which …

Glutathione-mediated release of functional miR-122 from gold nanoparticles for targeted induction of apoptosis in cancer treatment

Y Yuan, X Zhang, X Zeng, B Liu, F Hu… - … of Nanoscience and …, 2014 - ingentaconnect.com
MiRs was efficiently bound to water-soluble positively charged gold nanoparticles through
complementary electrostatic interaction. MiR-122 has been considered to be specifically …

[PDF][PDF] Silymarin Based Complexes-a mini Review

GA Paltinean, G Tomoaia, S Riga, A Mocanu… - Annals Series on …, 2022 - aos.ro
Silymarin (SIL) is a component extracted from Silybum marianum herb and is studied in
medicine due to its protective activities on certain organs (liver, kidney, heart, brain). The …

[PDF][PDF] Gold nanoparticles and chemotherapeutic agents

A AVRAM, G TOMOAIA, A MOCANU… - Annals of the Academy …, 2020 - academia.edu
Gold nanoparticles (AuNPs) receive a great deal of attention for biomedical applications due
to their unique properties to monitor intracellular delivery of therapeutic agents. Evidently …