The role of autophagy in retinal ganglion cell (RGC) death is still controversial. Several
studies focused on RGC body death, although the axonal degeneration pathway in the optic …

In our ever-aging world population, the risk of age-related neuropathies has been
increasing, representing both a social and economic burden to society. Since the ability to …

In healthy beings, age is the ultimate reason of cellular malfunction and death. In the rat
retina, age causes a functional decline and loss of specific neuronal populations. In this …

We determined whether the structural and functional integrity of amacrine cells (ACs), the
largest cohort of neurons in the mammalian retina, are affected in glaucoma. Intraocular …

Background: Degenerative changes caused by aging may affect the eye, especially the
retina. Such changes occur as a part of normal physiological process and may be …

The optic nerve is a white matter tract that conveys visual information to the brain. The sclera
comprises the white, protective outer layer of the eye. A characterization of the proteome of …

Purpose: To quantitatively investigate the microstructural properties of the optic nerve (ON)
in vivo using diffusion magnetic resonance imaging (dMRI) tractography in an elderly …

Aims: As individuals age, there is a known decline in visual function attributed to a reduction
in the optic nerve fibers and myelin sheath degeneration. Studies present conflicting findings …

Introduction: Optic nerves development begins throughout pregnancy and continues after
birth. Aging entails gradual degeneration of the structure and the number of the optic nerve …