The DNA methyltransferase (DNMT) family comprises a conserved set of DNA-modifying
enzymes that have a central role in epigenetic gene regulation. Recent studies have shown …

Addition of chemical tags on the DNA and modification of histone proteins impart a distinct
feature on chromatin architecture. With the advancement in scientific research, the key …

Historically, systemic self-inflammatory conditions were classified as either autoinflammatory
and caused by the innate immune system or autoimmune and driven by adaptive immune …

Among RNA modifications, transfer of methylgroups from the typical cofactor S‐adenosyl‐l‐
methionine by methyltransferases (MTases) to RNA is by far the most common reaction …

Epitranscriptomic mechanisms linking tRNA function and the brain proteome to cognition
and complex behaviors are not well described. Here, we report bi-directional changes in …

Sleep deprivation disrupts the lives of millions of people every day and has a profound
impact on the molecular biology of the brain. These effects begin as changes within a …

The broad application of next-generation sequencing technologies in conjunction with
improved bioinformatics has helped to illuminate the complexity of the transcriptome, both in …

Myeloid-derived suppressor cells (MDSCs) are identified as a highly heterogeneous group
of immature cells derived from bone marrow and play critical immunosuppressive functions …

Background Microsporidia are diverse spore forming, fungal-related obligate intracellular
pathogens infecting a wide range of hosts. This diversity is reflected at the genome level with …

DNA methyltransferases (DNMTs) are a group of proteins that catalyze DNA methylation by
transferring a methyl group to DNA. The genetic variation in DNMTs results in differential …