Biodegradable polymers in drug delivery and oral vaccination

P Jana, M Shyam, S Singh, V Jayaprakash… - European Polymer …, 2021 - Elsevier
Over the years biodegradable polymers have emerged as promising polymeric materials in
drug delivery and vaccination due to their fascinating properties like biocompatibility …

Immunotherapy and immunochemotherapy in combating visceral leishmaniasis

G Yadagiri, A Singh, K Arora, SL Mudavath - Frontiers in Medicine, 2023 - frontiersin.org
Visceral leishmaniasis (VL), a vector-borne disease, is caused by an obligate
intramacrophage, kinetoplastid protozoan parasite of the genus Leishmania. Globally, VL is …

Host–pathogen interaction in leishmaniasis: immune response and vaccination strategies

H Yasmin, A Adhikary, MN Al-Ahdal, S Roy, U Kishore - Immuno, 2022 - mdpi.com
Leishmaniasis is a zoonotic and vector-borne infectious disease that is caused by the genus
Leishmania belonging to the trypanosomatid family. The protozoan parasite has a digenetic …

Immunoinformatics Approach to Design a Multi-Epitope Nanovaccine against Leishmania Parasite: Elicitation of Cellular Immune Responses

M Margaroni, M Agallou, E Tsanaktsidou, O Kammona… - Vaccines, 2023 - mdpi.com
Leishmaniasis is a vector-borne disease caused by an intracellular parasite of the genus
Leishmania with different clinical manifestations that affect millions of people worldwide …

Virulence factors of Leishmania parasite: Their paramount importance in unraveling novel vaccine candidates and therapeutic targets

D Kumari, S Mahajan, P Kour, K Singh - Life sciences, 2022 - Elsevier
Leishmaniasis is a neglected tropical disease and remains a global concern for healthcare.
It is caused by an opportunistic protozoan parasite belonging to the genus Leishmania and …

Leishmania tarentolae: Taxonomic classification and its application as a promising biotechnological expression host

S Klatt, L Simpson, DA Maslov… - PLoS neglected tropical …, 2019 - journals.plos.org
In this review, we summarize the current knowledge concerning the eukaryotic protozoan
parasite Leishmania tarentolae, with a main focus on its potential for biotechnological …

The effects of silver nanoparticles biosynthesized using fig and olive extracts on cutaneous leishmaniasis-induced inflammation in female balb/c mice

MA Almayouf, M El-Khadragy, MA Awad… - Bioscience …, 2020 - portlandpress.com
Leishmaniasis is a group of infectious and noncontagious severe parasitic diseases, caused
by protozoans of the Leishmania genus. Natural products characterize a rich source of …

A targeted and protease-activated genetically encoded melittin-containing particle for the treatment of cutaneous and visceral leishmaniasis

M Habib, J Zheng, CF Chan, Z Yang… - … Applied Materials & …, 2024 - ACS Publications
Intracellular infections are difficult to treat, as pathogens can take advantage of intracellular
hiding, evade the immune system, and persist and multiply in host cells. One such …

Infection of Human Neutrophils With Leishmania infantum or Leishmania major Strains Triggers Activation and Differential Cytokines Release

R Oualha, M Barhoumi, S Marzouki… - Frontiers in cellular …, 2019 - frontiersin.org
Leishmaniases are neglected diseases, caused by intracellular protozoan parasites of the
Leishmania (L.) genus. Although the principal host cells of the parasites are macrophages …

Non-coding RNAs in the etiology and control of major and neglected human tropical diseases

O Tamgue, CF Mezajou, NN Ngongang… - Frontiers in …, 2021 - frontiersin.org
Non-coding RNAs (ncRNAs) including microRNAs (miRs) and long non-coding RNAs
(lncRNAs) have emerged as key regulators of gene expression in immune cells …