Image-guided radiotherapy for pelvic cancers: a review of current evidence and clinical utilisation

A Webster, AL Appelt, G Eminowicz - Clinical Oncology, 2020 - Elsevier
The meticulous selection and utilisation of image-guided radiotherapy (IGRT) are essential
for optimal radiotherapy treatment delivery when using highly conformal treatment …

Effect of intrafraction adaptation on PTV margins for MRI guided online adaptive radiotherapy for rectal cancer

CM Kensen, TM Janssen, A Betgen, L Wiersema… - Radiation …, 2022 - Springer
Purpose To determine PTV margins for intrafraction motion in MRI-guided online adaptive
radiotherapy for rectal cancer and the potential benefit of performing a 2nd adaptation prior …

Technological advances in radiotherapy of rectal cancer: opportunities and challenges

AL Appelt, D Sebag-Montefiore - Current opinion in oncology, 2016 - journals.lww.com
Few prospective studies of IMRT and VMAT exist, which causes uncertainty not just in
regards to the clinical benefit of these technologies but also in the optimal use. The priority …

A TCP-based early regression index predicts the pathological response in neo-adjuvant radio-chemotherapy of rectal cancer

C Fiorino, C Gumina, P Passoni, A Palmisano… - Radiotherapy and …, 2018 - Elsevier
Purpose Introducing a radiobiological index based on early tumor regression during neo-
adjuvant radio-chemotherapy (RCT, including oxaliplatin) of rectal adenocarcinoma and …

Knowledge-based automatic optimization of adaptive early-regression-guided VMAT for rectal cancer

R Castriconi, C Fiorino, P Passoni, S Broggi… - Physica Medica, 2020 - Elsevier
Purpose To implement a knowledge-based (KB) optimization strategy to our adaptive (ART)
early-regression guided boosting technique in neo-adjuvant radio-chemotherapy for rectal …

[HTML][HTML] Accurate outcome prediction after neo-adjuvant radio-chemotherapy for rectal cancer based on a TCP-based early regression index

C Fiorino, P Passoni, A Palmisano, C Gumina… - Clinical and …, 2019 - Elsevier
Background and purpose An early tumor regression index (ERI TCP) was previously
introduced and found to predict pathological response after neo-adjuvant radio …

Dosimetric benefit of an adaptive treatment by means of plan selection for rectal cancer patients in both short and long course radiation therapy

R De Jong, J Visser, KF Crama, N Van Wieringen… - Radiation …, 2020 - Springer
Background To compare target coverage and dose to the organs at risk in two approaches
to rectal cancer: a clinically implemented adaptive radiotherapy (ART) strategy using plan …

Is it time to introduce PET/CT in rectal cancer guidelines?

AM Maffione, G Montesi, P Caroli… - Clinical Nuclear …, 2020 - journals.lww.com
At the moment, international guidelines for rectal cancer suggest to consider 18 F-FDG
PET/CT scan in a few conditions:(1) at disease presentation in case of suspected or proven …

Predicting pathological response after radio-chemotherapy for rectal cancer: Impact of late oxaliplatin administration

S Broggi, P Passoni, C Gumina, A Palmisano… - Radiotherapy and …, 2020 - Elsevier
Background and purpose A previously introduced index based on early tumor (GTV)
regression (ERI TCP) during neo-adjuvant radio-chemotherapy of rectal cancer was used to …

The promise of adaptive radiotherapy for pelvic tumors:“too high cost for too little result” or “a low cost for a significant result”?

C Fiorino, C Cozzarini, P Passoni - Acta Oncologica, 2016 - Taylor & Francis
The sound and thorough review by Thornqvist et al.[1] on the clinical experience with
adaptive radiotherapy (ART) in the treatment of pelvic tumors arrives in a ''hot''and quite …