The 18 kDa translocator protein (TSPO) is a highly conserved protein located in the outer
mitochondrial membrane. TSPO binding, as measured with positron emission tomography …

For over 15 years, the peripheral benzodiazepine receptor (PBR), recently named
translocator protein 18 kDa (TSPO) has been studied as a biomarker of reactive gliosis and …

The mitochondrial benzodiazepine receptor (mBzR) has been solubilized with retention of
reversible ligand binding, and the associated subunits were characterized. mBzR comprises …

The 18 kDa translocator protein (TSPO), previously known as the peripheral
benzodiazepine receptor, is expressed in the injured brain. It has become known as an …

For over 20 years, numerous investigations have focused on elucidating the function of the
peripheral benzodiazepine receptor (PBR). This relatively small protein (18kDa) arouses …

Steroidogenesis begins with the metabolism of cholesterol to pregneolone by the inner
mitochondrial membrane cytochrome P450 side-chain cleavage (P450scc) enzyme. The …

In previous studies we demonstrated that peripheral-type benzodiazepine receptors (PBR)
were coupled to steroidogenesis in several adrenocortical and Leydig cell systems (Mukhin …

Diazepam binding inhibitor (DBI) is a 9-kD polypeptide that was first isolated in 1983 from rat
brain by monitoring its ability to displace diazepam from the benzodiazepine (BZD) …

We report the construction of the first complete genetic linkage map of the laboratory rat. By
testing 1171 simple sequence length polymorphisms (SSLPs), we have identified 432 …

Allopregnanolone is synthesized in the central nervous system either de novo from
cholesterol or from steroid hormone precursors like progesterone and pregnenolone. Over …