Metastasis accounts for more than 90% of cancer related mortality, thus the most pressing
need in the field of oncology today is the ability to accurately predict future onset of …

Disorders of the anterior segment of the eye encompass a variety of clinical presentations
including aniridia, Axenfeld and Rieger anomalies, primary congenital glaucoma, Peters …

Posterior urethral valves (PUV) are the commonest cause of end-stage renal disease in
children, but the genetic architecture of this rare disorder remains unknown. We performed a …

Atrioventricular septal defect (AVSD) may occur as part of a complex disorder (eg, Down
syndrome, heterotaxy), or as isolate cardiac defect. Multiple lines of evidence support a role …

Exposure to perfluorooctanesulfonic acid (PFOS) has been associated with congenital heart
disease (CHD) and decreased birth weight. PFOS exposure can disrupt signaling pathways …

Many forms of childhood glaucoma have been associated with underlying genetic changes,
and variants in many genes have been described. Currently, testing is variable as there are …

Purpose Mutations were previously identified in the CYP1B1 gene in six out of 18 Lebanese
families (33%) with primary congenital glaucoma (PCG). The purpose of this study is to …

Glaucoma is a series of linked optic diseases resulting in progressive vision loss and total
blindness due to the acquired loss of retinal ganglion cells. This harm to the optic nerve …

Objective Deleterious genetic variants comprise one cause of cardiac conotruncal defects
(CTDs). Genes associated with CTDs are gradually being identified. In the present study, we …

Abstract The Middle East and North Africa regions, including Lebanon, have recently
witnessed rapid urbanization and modernization over the last couple of decades that has led …