Organotins (IV) exhibit significant in vitro anti-proliferative activity, while the in vivo tests are
encouraging. The recent reports on the anti-proliferative activity of organotin (IV) compounds …

For more than 100 years metal complexes have been extensively used in therapy and since
the discovery of cisplatin the research in this field has expanded exponentially. The scientific …

Four new carboxylates complexes with general formula R2SnL2 and R3SnL, where R= n-
butyl (1, 3), methyl (2, 4) and L= 4-Chlorophenoxyacetate, were synthesized in significant …

Three different multifunctional nanosystems based on the tethering onto mesoporous silica
nanoparticles (MSN) of different fragments such as an organotin-based cytotoxic compound …

To validate the effect of metal ions in analogous ligand scaffolds on DNA binding and
cytotoxic response, we have synthesized a series of water-soluble ionic N …

The strong therapeutic potential of an organotin (IV) compound loaded in nanostructured
silica (SBA‐15pSn) is demonstrated: B16 melanoma tumor growth in syngeneic C57BL/6 …

Cancer is a multistep disease incorporating physical, chemical, environmental, metabolic
and genetic factors, which play direct or indirect role in the induction and deterioration of …

Organotin (IV) compounds are used globally as stabilizers, catalyzers and biocidal agents.
However, due to the increased focus on the application of organotin (IV) compounds in …

This article reviews recent studies of platinum and other metal-containing antitumor drugs in
preclinical development. A short overview of the development of cisplatin-based drug …

In this work, three new di-and tri-organotin (IV) complex Ph 3 SnL, Bu 3 SnL, and Me 2 SnL 2
were successfully synthesized by reacting sulfamethoxazole drug as a ligand with different …