There has been a significant progress in our understanding of the molecular mechanisms by
which calcium (Ca2+) ions mediate various types of cardiac arrhythmias. A growing list of …

Eukaryotic cells have been confronted throughout their evolution with potentially lethal
plasma membrane injuries, including those caused by osmotic stress, by infection from …

The plasma membrane in eukaryotic cells contains microdomains that are enriched in
certain glycosphingolipids, gangliosides, and sterols (such as cholesterol) to form …

Cardiac-specific troponins are elevated in blood following cardiac injury and are the
preferred diagnostic biomarkers when acute myocardial infarction is suspected clinically …

Disruption of the plasma membrane often accompanies cellular injury, and in muscle,
plasma membrane resealing is essential for efficient recovery from injury. Muscle …

Skeletal muscle is the largest organ of human body with several important roles in everyday
movement and metabolic homeostasis. The limited ability of small animal models of muscle …

Background Cachexia, a multifactorial syndrome affecting more than 50% of patients with
advanced cancer and responsible for~ 20% of cancer‐associated deaths, is still a poorly …

Dystrophin deficiency is the genetic basis for Duchenne muscular dystrophy (DMD), but the
cellular basis of progressive myofiber death in DMD is not fully understood. Using two …

Glucocorticoid steroids such as prednisone are prescribed for chronic muscle conditions
such as Duchenne muscular dystrophy, where their use is associated with prolonged …

Plasma membrane repair is a conserved cellular response mediating active resealing of
membrane disruptions to maintain homeostasis and prevent cell death and progression of …