Brain tumors are particularly challenging malignancies, due to their location in a structurally
and functionally distinct part of the human body–the central nervous system (CNS). The CNS …

Acoustically driven bubbles produce a range of mechanical, thermal and chemical effects
that can be exploited in drug delivery applications. Significant improvements in the targeting …

Recently, emerging evidence has demonstrated that cavitation actually creates important
bidirectional channels on biological barriers for both intratumoral drug delivery and …

Objective: Passive acoustic mapping (PAM) provides the spatial information of acoustic
energy emitted from microbubbles during focused ultrasound (FUS), which can be used for …

Acoustic cavitation plays a critical role in various biomedical applications. However,
uncontrolled cavitation can lead to undesired damage to healthy tissues. Therefore, real …

Focused ultrasound (FUS)-induced cavitation-mediated brain therapies have become
emerging therapeutic modalities for neurologic diseases. Cavitation monitoring is essential …

Ultrasonically actuated microbubble oscillations hold great promise for minimally invasive
therapeutic interventions. However for their successful translation to the clinic, real-time …

Sources of nonlinear acoustic emissions, particularly those associated with cavitation
activity, play a key role in the safety and efficacy of current and emerging therapeutic …

Ultrasonic cavitation, characterized by the oscillation or abrupt collapse of cavitation nuclei
in response to ultrasound stimulation, plays a significant role in various applications within …

Passive cavitation imaging (PCI) with a clinical diagnostic array results in poor axial
localization of bubble activity due to the size of the point spread function (PSF). The …