RNA-mediated immunotherapy regulating tumor immune microenvironment: next wave of cancer therapeutics

PR Pandey, KH Young, D Kumar, N Jain - Molecular cancer, 2022 - Springer
Accumulating research suggests that the tumor immune microenvironment (TIME) plays an
essential role in regulation of tumor growth and metastasis. The cellular and molecular …

[HTML][HTML] RNA nanotechnology-mediated cancer immunotherapy

YX Lin, Y Wang, S Blake, M Yu, L Mei, H Wang… - Theranostics, 2020 - ncbi.nlm.nih.gov
RNA molecules (eg, siRNA, microRNA, and mRNA) have shown tremendous potential for
immunomodulation and cancer immunotherapy. They can activate both innate and adaptive …

Theranostic nanoparticles for RNA-based cancer treatment

RA Revia, ZR Stephen, M Zhang - Accounts of Chemical research, 2019 - ACS Publications
Conspectus Certain genetic mutations lead to the development of cancer through
unchecked cell growth and division. Cancer is typically treated through surgical resection …

[HTML][HTML] Gold nanoparticle-based platforms for vaccine development

RM Ferrando, L Lay, L Polito - Drug Discovery Today: Technologies, 2020 - Elsevier
Since their discovery, therapeutic or prophylactic vaccines represent a promising option to
prevent or cure infections and other pathologies, such as cancer or autoimmune disorders …

Photothermal effect of gold nanoparticles as a nanomedicine for diagnosis and therapeutics

PPP Kumar, DK Lim - Pharmaceutics, 2023 - mdpi.com
Gold nanoparticles (AuNPs) have received great attention for various medical applications
due to their unique physicochemical properties. AuNPs with tunable optical properties in the …

Inorganic nanomaterial‐mediated gene therapy in combination with other antitumor treatment modalities

G Lin, RA Revia, M Zhang - Advanced functional materials, 2021 - Wiley Online Library
Cancer is a genetic disease originating from the accumulation of gene mutations in a
cellular subpopulation. Although many therapeutic approaches have been developed to …

[HTML][HTML] Advancing cancer immunotherapy through siRNA-based gene silencing for immune checkpoint blockade

Y Choi, SH Seok, HY Yoon, JH Ryu, IC Kwon - Advanced Drug Delivery …, 2024 - Elsevier
Cancer immunotherapy represents a revolutionary strategy, leveraging the patient's immune
system to inhibit tumor growth and alleviate the immunosuppressive effects of the tumor …

Amphetamine decorated cationic lipid nanoparticles cross the blood–brain barrier: Therapeutic promise for combating glioblastoma

S Saha, V Yakati, G Shankar… - Journal of Materials …, 2020 - pubs.rsc.org
Combating brain tumors (glioblastoma multiforme or GBM) is a formidable challenge
because of the existence of blood–brain barrier (BBB), a tight cellular junction that separates …

Improving anti-tumour efficacy of PEGylated liposomal doxorubicin by dual targeting of tumour cells and tumour endothelial cells using anti-p32 CGKRK peptide

M Mashreghi, M Faal Maleki, M Karimi… - Journal of drug …, 2021 - Taylor & Francis
The aim of this study was to surface-functionalize PEGylated liposomal doxorubicin (PLD)
using anti-p32 CGKRK peptide to evaluate its anti-angiogenic and anti-tumour activities …

Smartly engineered casein manganese oxide nanobiomaterials and its potential therapeutic angiogenesis applications for wound healing and limb ischemia

S Haque, R Kotcherlakota, P Bhamidipati… - Advanced …, 2023 - Wiley Online Library
Recent research offers several approaches for the advancement of manganese‐based
nanomaterials for its therapeutic use. The present research paper reports the development …