Proteins that self-assemble into polyhedral shell-like structures are useful molecular
containers both in nature and in the laboratory. Here we review efforts to repurpose diverse …

Our ability to detect, image, and quantify nanoscopic objects and molecules with visible light
has undergone dramatic improvements over the past few decades. While fluorescence has …

We review approaches aimed at deciphering the physical mechanisms responsible for viral
structure and assembly. We discuss the basic principles of condensed matter physics …

Interferometric scattering (iSCAT) microscopy is a label-free optical method capable of
detecting single proteins, localizing their binding positions with nanometer precision, and …

Viral capsids are often regarded as inert structural units, but in actuality they display
fascinating dynamics during different stages of their life cycle. With the advent of single …

Molecular self-assembly is pervasive in the formation of living and synthetic materials.
Knowledge gained from research into the principles of molecular self-assembly drives …

Biothermodynamics of viruses is among the youngest but most rapidly developing scientific
disciplines. During the COVID-19 pandemic, it closely followed the results published by …

Virus-like particles (VLPs) are increasingly used for vaccine development and drug delivery.
Assembly of VLPs from purified monomers in a chemically defined reaction is advantageous …

SARS-CoV-2 belongs to the group of RNA viruses with a pronounced tendency to mutate.
Omicron BA. 2.75 is a subvariant believed to be able to suppress the currently dominant BA …

Recombinant adeno-associated viruses (rAAV) are used extensively as gene delivery
vectors in clinical studies, and several rAAV based treatments have already been approved …