Cocaine (Figure 1) abuse is growing at an alarming rate in the United States. Currently, we
are experiencing its third epidemic. The two prior epidemics occurred in the 1890's and in …

Carbonyl compounds undergo α‐alkylation via the corresponding silyl enol ethers using
SN1 active alkyl halides or acetates in the presence of Lewis acids. This methodology …

The importance of tandem reactions is evident--besides their pragmatic value, they have an
aesthetic appeal. The author presents a survey of these reactions that will rivet the attention …

Conclusion Despite numerous efforts over the years, the biosynthesis of TTX remains a
mystery. All conventional approaches to the biosynthetic studies, including feeding …

α, β-β, γ-unsaturated esters can be converted by strong base and chlorotrimethylsilane to
the corresponding mixed vinylketene acetals which are shown to be particularly useful and …

The synthesis of complex natural products still remains as the bottleneck for the biological
evaluation of such compounds. In contrast to the biosyntheses, vinylogous aldol reactions …

An extensive phytochemical study of a foliose lichen from Indonesia, Parmelia cetrata,
resulted in the successful isolation of 13 phenol and depside derivatives (1–13) including …

Enantioselective Total Synthesis of Callipeltoside A | Journal of the American Chemical
Society ACS ACS Publications C&EN CAS Find my institution Log In Journal of the …

A new strategy for the synthesis of 3, 5-disubstituted phenols is established through one-pot
Robinson annulation of α, β-unsaturated ketones with α-fluoro-β-ketoesters followed by in …

The synthesis of substituted aromatic hydrocarbons has been a feature of synthetic organic
chemistry from almost its beginnings early in the nineteenth century and owes much to the …