The discovery of the sensory nature of the carotid body dates back to the beginning of the
20th century. Following these seminal discoveries, research into carotid body mechanisms …

Sleep is a major physiological drive. The average child spends almost one-half of his or her
life asleep. A newborn will sleep for as much as 16 ha day. Thus, respiratory disorders …

Rationale Evidence regarding exercise capacity and physical activity in children born
extremely preterm (EP) is limited. Since survivors remain at high risk for developing …

It is well-established that environmental and biological risk factors contribute to Sudden
Infant Death Syndrome (SIDS). There is also growing consensus that SIDS requires the …

Obstructive sleep apnea (OSA) is an increasingly recognized, common chronic disease in
the developed nations and is a complex disease that has high social and economic costs …

Intermittent hypoxic episodes are typically a consequence of immature respiratory control
and remain a troublesome challenge for the neonatologist. Furthermore, their frequency and …

Preterm birth temporarily disrupts autonomic nervous system (ANS) development, and the
long‐term impacts of disrupted fetal development are unclear in children. Abnormal cardiac …

Apnoea and periodic breathing are the hallmarks of breathing for the infant who is born
prematurely. Sustained respiration is obtained through modulation of respiratory-related …

Hypoxic episodes remain a major source of frustration for care providers of preterm infants in
the neonatal intensive care unit. Although optimizing oxygen saturation remains a …

OBJECTIVES: Previously published data from the Cleveland Children's Sleep and Health
Study demonstrated that preterm infants are especially vulnerable both to sleep disordered …