Raman spectroscopy: an evolving technique for live cell studies
One of the most exciting developments in Raman spectroscopy in the last decade has been
its application to cells and tissues for diagnostic and pharmaceutical applications, and in …
its application to cells and tissues for diagnostic and pharmaceutical applications, and in …
Clinical applications of infrared and Raman spectroscopy: state of play and future challenges
Vibrational spectroscopies, based on infrared absorption and/or Raman scattering provide a
detailed fingerprint of a material, based on the chemical content. Diagnostic and prognostic …
detailed fingerprint of a material, based on the chemical content. Diagnostic and prognostic …
Microsecond fingerprint stimulated Raman spectroscopic imaging by ultrafast tuning and spatial-spectral learning
Label-free vibrational imaging by stimulated Raman scattering (SRS) provides
unprecedented insight into real-time chemical distributions. Specifically, SRS in the …
unprecedented insight into real-time chemical distributions. Specifically, SRS in the …
[HTML][HTML] An evaluation of fixation methods: Spatial and compositional cellular changes observed by Raman imaging
AJ Hobro, NI Smith - Vibrational Spectroscopy, 2017 - Elsevier
Although live cell imaging is desirable, it is not always feasible and in many situations cells
are fixed in order to provide a 'snapshot'of the nature and distribution of molecules within a …
are fixed in order to provide a 'snapshot'of the nature and distribution of molecules within a …
Standardization of complex biologically derived spectrochemical datasets
CLM Morais, M Paraskevaidi, L Cui, NJ Fullwood… - Nature protocols, 2019 - nature.com
Spectroscopic techniques such as Fourier-transform infrared (FTIR) spectroscopy are used
to study interactions of light with biological materials. This interaction forms the basis of …
to study interactions of light with biological materials. This interaction forms the basis of …
Raman spectroscopy: guiding light for the extracellular matrix
The extracellular matrix (ECM) consists of a complex mesh of proteins, glycoproteins, and
glycosaminoglycans, and is essential for maintaining the integrity and function of biological …
glycosaminoglycans, and is essential for maintaining the integrity and function of biological …
Understanding the molecular information contained in principal component analysis of vibrational spectra of biological systems
F Bonnier, HJ Byrne - Analyst, 2012 - pubs.rsc.org
K-means clustering followed by Principal Component Analysis (PCA) is employed to
analyse Raman spectroscopic maps of single biological cells. K-means clustering …
analyse Raman spectroscopic maps of single biological cells. K-means clustering …
Accurate tumor subtype detection with raman spectroscopy via variational autoencoder and machine learning
Accurate diagnosis of cancer subtypes is a great guide for the development of surgical plans
and prognosis in the clinic. Raman spectroscopy, combined with the machine learning …
and prognosis in the clinic. Raman spectroscopy, combined with the machine learning …
Optimization of fixation methods for observation of bacterial cell morphology and surface ultrastructures by atomic force microscopy
Y Chao, T Zhang - Applied microbiology and biotechnology, 2011 - Springer
Fixation ability of five common fixation solutions, including 2.5% glutaraldehyde, 10%
formalin, 4% paraformaldehyde, methanol/acetone (1: 1), and ethanol/acetic acid (3: 1) were …
formalin, 4% paraformaldehyde, methanol/acetone (1: 1), and ethanol/acetic acid (3: 1) were …
Quantitative chemometric phenotyping of three-dimensional liver organoids by Raman spectral imaging
V LaLone, A Aizenshtadt, J Goertz, FS Skottvoll… - Cell Reports …, 2023 - cell.com
Confocal Raman spectral imaging (RSI) enables high-content, label-free visualization of a
wide range of molecules in biological specimens without sample preparation. However …
wide range of molecules in biological specimens without sample preparation. However …