NF-κB (nuclear factor kappa B) belongs to a family of transcription factors known to regulate
a broad range of processes such as immune cell function, proliferation and cancer …

NF-κB, a transcription factor first discovered in 1986, is now known to be closely connected
to the process of tumorogenesis based on a multiplicity of evidence.(1) NF-κB is activated in …

Oxidative stress is considered causal of aging and pathological cell death, however, very
little is known about its function in the natural processes that support the formation of an …

Although human pathologies have mostly been modeled using higher mammal systems
such as mice, the lower vertebrate zebrafish has gained tremendous attention as a model …

Innate immunity comprises several inflammation-related modulatory pathways which receive
signals from an array of membrane-bound and cytoplasmic pattern recognition receptors …

It has become increasingly clear that deregulation of the NF κ B signaling cascade is a
common underlying feature of many human ailments including cancers. The past two …

BACKGROUND & AIMS: The nuclear factor κ-light-chain enhancer of activated B cells (NF-
κB) transcription factor pathway is activated in response to diverse microbial stimuli to …

Inflammatory signaling has been shown to be essential for stress hematopoiesis in adult
bone marrow, either through increasing proliferation or by directing differentiation of …

The NF-κB (nuclear factor κB) family of transcription factors are involved in a myriad of
activities, including the regulation of immune responses, maturation of immune cells …

The innate immune response involves a concerted network of induced gene products,
preformed immune effectors, biochemical signalling cascades and specialised cells …