Recent developments in blood biomarkers in neuro-oncology

JB Foster, MP Koptyra, SJ Bagley - Current Neurology and Neuroscience …, 2023 - Springer
Abstract Purpose of Review Given the invasive and high-risk nature of brain surgery, the
need for non-invasive biomarkers obtained from the peripheral blood is greatest in tumors of …

Molecular neuropathology: an essential and evolving toolbox for the diagnosis and clinical management of central nervous system tumors

L Bertero, L Mangherini, AA Ricci, P Cassoni, F Sahm - Virchows Archiv, 2024 - Springer
Molecular profiling has transformed the diagnostic workflow of CNS tumors during the last
years. The latest WHO classification of CNS tumors (5th edition), published in 2021, pushed …

Sequencing of cerebrospinal fluid cell-free DNA facilitated early differential diagnosis of intramedullary spinal cord tumors

R Chai, S An, H Lin, B Pang, H Yan, Y Liu, Y Wu… - NPJ Precision …, 2024 - nature.com
Pre-surgery differential diagnosis is valuable for personalized treatment planning in
intramedullary spinal cord tumors. This study assessed the performance of sequencing cell …

Synergising hydrothermal pre-treatment and biological processes for enhancing biohydrogen production from palm oil mill effluent

BS Zainal, KL Yu, HC Ong, H Mohamed, PJ Ker… - Process Safety and …, 2024 - Elsevier
The high quantity of nutrient-rich palm oil mill effluent (POME) waste in the industry will have
a severe negative environmental impact and a high cost of treatment. However, POME …

An 8q24 gain in pancreatic juice is a candidate biomarker for the detection of pancreatic cancer

IJM Levink, MI Srebniak, WG De Valk… - International Journal of …, 2023 - mdpi.com
Secretin-stimulated pancreatic juice (PJ), collected from the duodenum, presents a valuable
biomarker source for the (earlier) detection of pancreatic cancer (PC). Here, we evaluate the …

Rational combination platform trial design for children and young adults with diffuse midline glioma: A report from PNOC

S Mueller, C Kline, A Franson, J van der Lugt… - Neuro …, 2024 - academic.oup.com
Background Diffuse midline glioma (DMG) is a devastating pediatric brain tumor
unresponsive to hundreds of clinical trials. Approximately 80% of DMGs harbor H3K27M …

Recent Advancements and Innovations in Pediatric Precision Oncology

R Mangum, FY Lin, DW Parsons - Journal of Pediatric Hematology …, 2024 - journals.lww.com
Precision oncology incorporates comprehensive genomic profiling into the individualized
clinical care of pediatric cancer patients. In recent years, comprehensive pan-cancer …

Cerebrospinal fluid-derived genomic alterations tracking glioma

Z Zhu, Y Yu, F Liu, X Yang, Z Zhou, Z Zhu, Z Wang - 2024 - researchsquare.com
Background Diffuse gliomas, characterized by significant heterogeneity, are aggressive
brain tumors that commonly harbor oncogenic mutations. Examining the evolutionary …

Учредители: Национальный медицинский исследовательский центр онкологии им. НН Петрова

ЕШ КУЛИГИНА, ГА ЯНУС, АС МАРТЬЯНОВ… - ВОПРОСЫ …, 2023 - elibrary.ru
Концентрация циркулирующих опухолевых ДНК (цоДНК) в крови является
чувствительным и специфичным маркером для мониторинга в режиме реального …