Mitochondria are well known as organelles responsible for the maintenance of cellular
bioenergetics through the production of ATP. Although oxidative phosphorylation may be …

Mitochondria are highly dynamic organelles and important for a variety of cellular functions.
They constantly undergo fission and fusion events, referred to as mitochondrial dynamics …

Mitochondrial DNA (mtDNA) escaping stressed mitochondria provokes inflammation via
cGAS-STING pathway activation and, when oxidized (Ox-mtDNA), it binds cytosolic NLRP3 …

Abstract FUN14 domain-containing protein 1 (Fundc1)-dependent mitophagy, mainly
activated by ischemic/hypoxic preconditioning, benefits acute myocardial reperfusion injury …

Most cellular stress responses converge on the mitochondria. Consequently, the
mitochondria must rapidly respond to maintain cellular homeostasis and physiological …

Recent reports indicated that mitophagy protects against alcohol-induced liver injury, which
helps remove damaged mitochondria to reduce the accumulation of reactive oxygen species …

The large cytosolic GTPase, dynamin-related protein 1 (Drp1), mediates both physiological
and pathological mitochondrial fission. Cell stress triggers Drp1 binding to mitochondrial …

Our recent study has shown that prenatal exposure to bisphenol A (BPA) altered the
expression of genes associated with autism spectrum disorder (ASD). In this study, we …

Mitochondria release many damage-associated molecular patterns (DAMPs) when cells are
damaged or stressed, with mitochondrial DNA (mtDNA) being. MtDNA activates innate …

Arterial media calcification is related to mitochondrial dysfunction. Protective mitophagy
delays the progression of vascular calcification. We previously reported that lactate …