The voltage-gated potassium channel KV 1.3 is a well-established therapeutic target for a
range of autoimmune diseases, in addition to being the site of action of many venom-derived …

Scorpion toxins have been the subject of many studies exploring their pharmacological
potential. The high affinity and the overall selectivity to various types of ionic channels …

Sea anemone venom is rich in bioactive compounds, including peptides containing multiple
disulfide bridges. In a transcriptomic study on Oulactis sp., we identified the putative 36 …

This study investigated geographic variability in the venom of Centruroides sculpturatus
scorpions from different biotopes. Venom from scorpions collected from two different regions …

Ion channels play pivotal role in the physiological and pathological function of immune cells.
As immune cells represent a functionally diverse population, subtype-specific functional …

Scorpion venom contains various bioactive peptides, many of which exhibit insecticidal
activity. The majority of these peptides have a cystine-stabilized α-helix/β-sheet (CSαβ) …

Over two-thirds of a century ago, Hodgkin and Huxley proposed the existence of voltage
gated ion channels (VGICs) to carry Na+ and K+ ions across the cell membrane to create the …

Canais iônicos são os elementos essenciais da excitabilidade da membrana, responsáveis
pela transmissão e transdução de sinais em neurônios, sendo esses canais passíveis de …

Les produits d'origine naturelle sont de plus en plus recherchés et testés pour leur potentiel
thérapeutique. Les peptides issus de venins de scorpions capables de moduler l'activité des …

Потенциал-чувствительные калиевые каналы (KV-каналы)—важная группа калиевых
каналов (К+-каналов), участвующая в различных процессах, таких как передача …