All life forms have evolved under the constant force of gravity on Earth and developed ways to counterbalance acceleration load. In space, shear forces, buoyance-driven convection …
Cancer is a disease exhibiting uncontrollable cell growth and spreading to other parts of the organism. It is a heavy, worldwide burden for mankind with high morbidity and mortality …
P Bradbury, H Wu, JU Choi, AE Rowan… - Frontiers in cell and …, 2020 - frontiersin.org
A lack of gravity experienced during space flight has been shown to have profound effects on human physiology including muscle atrophy, reductions in bone density and immune …
Microgravity (µ g) has a massive impact on the health of space explorers. Microgravity changes the proliferation, differentiation, and growth of cells. As crewed spaceflights into …
D Grimm, M Wehland, J Pietsch… - … Engineering Part B …, 2014 - liebertpub.com
Tissue engineering in simulated (s-) and real microgravity (r-μ g) is currently a topic in Space medicine contributing to biomedical sciences and their applications on Earth. The principal …
Experiments conducted in the microgravity environment of space are not typically at the forefront of the mind of a cancer biologist. However, space provides physical conditions that …
With the increasing number of spaceflights, it is crucial to understand the changes occurring in human cells exposed to real microgravity (r-µ g) conditions. We tested the effect of r-µ g on …
TJ Corydon, S Kopp, M Wehland, M Braun, A Schütte… - Scientific reports, 2016 - nature.com
Microgravity induces changes in the cytoskeleton. This might have an impact on cells and organs of humans in space. Unfortunately, studies of cytoskeletal changes in microgravity …
Glioblastoma multiforme (GBM) is one of the most aggressive malignant brain tumors and urgently requires the development of new therapeutic strategies. In this study, an innovative …