The role of oxidative stress in the pathophysiology of gestational diabetes mellitus
M Lappas, U Hiden, G Desoye, J Froehlich… - Antioxidants & redox …, 2011 - liebertpub.com
Normal human pregnancy is considered a state of enhanced oxidative stress. In pregnancy,
it plays important roles in embryo development, implantation, placental development and …
it plays important roles in embryo development, implantation, placental development and …
Adenosine signalling in diabetes mellitus—pathophysiology and therapeutic considerations
Adenosine is a key extracellular signalling molecule that regulates several aspects of tissue
function by activating four G-protein-coupled receptors, A1, A2A, A2B and A1 adenosine …
function by activating four G-protein-coupled receptors, A1, A2A, A2B and A1 adenosine …
Molecular pathways disrupted by gestational diabetes mellitus
C Nguyen-Ngo, N Jayabalan… - Journal of molecular …, 2019 - jme.bioscientifica.com
Gestational diabetes mellitus (GDM) imposes serious short-and long-term health problems
for mother and baby. An effective therapeutic that can reduce the incidence of GDM and …
for mother and baby. An effective therapeutic that can reduce the incidence of GDM and …
Normal glucose uptake in the brain and heart requires an endothelial cell-specific HIF-1α–dependent function
Although intimately positioned between metabolic substrates in the bloodstream and the
tissue parenchymal cells that require these substrates, a major role of the vascular …
tissue parenchymal cells that require these substrates, a major role of the vascular …
Differential placental macrovascular and microvascular endothelial dysfunction in gestational diabetes
L Sobrevia, F Abarzúa, JK Nien, C Salomón… - Placenta, 2011 - Elsevier
Human endothelial dysfunction is a common feature in many diseases of pregnancy, such
as gestational diabetes (GD). Metabolic changes include abnormal synthesis of nitric oxide …
as gestational diabetes (GD). Metabolic changes include abnormal synthesis of nitric oxide …
Insulin restores gestational diabetes mellitus–reduced adenosine transport involving differential expression of insulin receptor isoforms in human umbilical vein …
OBJECTIVE To determine whether insulin reverses gestational diabetes mellitus (GDM)–
reduced expression and activity of human equilibrative nucleoside transporters 1 (hENT1) in …
reduced expression and activity of human equilibrative nucleoside transporters 1 (hENT1) in …
Fetoplacental vascular endothelial dysfunction as an early phenomenon in the programming of human adult diseases in subjects born from gestational diabetes …
Gestational diabetes mellitus (GDM) and obesity in pregnancy (OP) are pathological
conditions associated with placenta vascular dysfunction coursing with metabolic changes …
conditions associated with placenta vascular dysfunction coursing with metabolic changes …
Assessment of endothelial function in pregnant women with preeclampsia and gestational diabetes mellitus by flow-mediated dilation of brachial artery
MFB de Resende Guimarães, AHF Brandão… - Archives of gynecology …, 2014 - Springer
Purpose To compare endothelial function, as assessed by flow-mediated dilation (FMD) in
pregnant women with preeclampsia (PE), gestational diabetes mellitus (GDM) and healthy …
pregnant women with preeclampsia (PE), gestational diabetes mellitus (GDM) and healthy …
Materno-fetal cholesterol transport during pregnancy
S Kallol, C Albrecht - Biochemical Society Transactions, 2020 - portlandpress.com
Cholesterol is a major nutrient required for fetal growth. It is also a precursor for the
synthesis of steroid hormones and essential for the development and maturation of fetal …
synthesis of steroid hormones and essential for the development and maturation of fetal …
Nitric oxide is a central common metabolite in vascular dysfunction associated with diseases of human pregnancy
Preeclampsia (PE), gestational diabetes mellitus (GDM), and maternal supraphysiological
hypercholesterolaemia (MSPH) are pregnancy-related conditions that cause metabolic …
hypercholesterolaemia (MSPH) are pregnancy-related conditions that cause metabolic …