Simple Summary Only about 4% of thyroid nodules are carcinomas and require surgery.
Fine-needle aspiration cytology is the most accurate tool to distinguish benign from …

Advances in the molecular characterization of thyroid cancers have fueled the development
of genetic and gene expression‐based tests for thyroid fine‐needle aspirations. Collectively …

Objective: To develop evidence-based recommendations for safe, effective, and appropriate
thyroidectomy. Background: Surgical management of thyroid disease has evolved …

Thyroid nodules are detected in up to 50 to 60% of healthy subjects. Most nodules do not
cause clinically significant symptoms, and as a result, the main challenge in their …

Background Approximately 25% of thyroid nodule fine‐needle aspirates (FNAs) have
cytology that is indeterminate for malignant disease. Accurate risk stratification of these …

Molecular fine-needle aspiration (FNA) cytology diagnostics has the potential to address the
inherent limitation of FNA cytology which is an indeterminate (atypia of undetermined …

Background: Molecular testing for oncogenic gene mutations and chromosomal
rearrangements plays a growing role in the optimal management of thyroid nodules, yet …

Key Clinical Points Thyroid Nodules Thyroid nodules are common; the majority are benign.
Thyroid ultrasonographic characteristics and especially the results of ultrasonographically …

Context.—Fine-needle aspiration of thyroid nodules is a reliable diagnostic method to
determine the nature of thyroid nodules. Nonetheless, indeterminate cytology diagnoses …

Background: Molecular testing of thyroid nodules is increasingly being utilized to guide
clinical management decisions. RAS mutations are the most frequent mutations detected in …