MicroRNAs as biomarkers for early breast cancer diagnosis, prognosis and therapy prediction

FJ Nassar, R Nasr, R Talhouk - Pharmacology & therapeutics, 2017 - Elsevier
Breast cancer is a major health problem that affects one in eight women worldwide. As such,
detecting breast cancer at an early stage anticipates better disease outcome and prolonged …

MicroRNA expression profiles and type 1 diabetes mellitus: systematic review and bioinformatic analysis

TS Assmann, M Recamonde-Mendoza… - Endocrine …, 2017 - ec.bioscientifica.com
Growing evidence indicates that microRNAs (miRNAs) have a key role in processes
involved in type 1 diabetes mellitus (T1DM) pathogenesis, including immune system …

Candidate miRNAs in human breast cancer biomarkers: a systematic review

M Adhami, AA Haghdoost, B Sadeghi… - Breast Cancer, 2018 - Springer
Background Breast cancer (BC) is the most prevalent cancer and the main cause of cancer
deaths among females around the world. For early diagnosis of BC, there would be an …

MicroRNAs as biomarker for breast cancer

T Aggarwal, R Wadhwa, R Gupta… - … Metabolic & Immune …, 2020 - ingentaconnect.com
Regardless of advances in detection and treatment, breast cancer affects about 1.5 million
women all over the world. Since the last decade, genome-wide association studies (GWAS) …

Machine learning-based ensemble recursive feature selection of circulating mirnas for cancer tumor classification

A Lopez-Rincon, L Mendoza-Maldonado… - Cancers, 2020 - mdpi.com
Circulating microRNAs (miRNA) are small noncoding RNA molecules that can be detected
in bodily fluids without the need for major invasive procedures on patients. miRNAs have …

Differential microRNA expression in breast cancer with different onset age

HP Tsai, SF Huang, CF Li, HT Chien, SC Chen - PLoS One, 2018 - journals.plos.org
Purpose The lower breast cancer incidence in Asian populations compared with Western
populations has been speculated to be caused by environmental and genetic variation …

Breast cancer in young women: status quo and advanced disease management by a predictive, preventive, and personalized approach

E Kudela, M Samec, P Kubatka, M Nachajova… - Cancers, 2019 - mdpi.com
Why does healthcare of breast cancer (BC) patients, especially in a young population,
matter and why are innovative strategies by predictive, preventive, and personalized …

Identifying potential circulating miRNA biomarkers for the diagnosis and prediction of ovarian cancer using machine-learning approach: application of Boruta

F Hamidi, N Gilani, R Arabi Belaghi… - Frontiers in Digital …, 2023 - frontiersin.org
Introduction In gynecologic oncology, ovarian cancer is a great clinical challenge. Because
of the lack of typical symptoms and effective biomarkers for noninvasive screening, most …

Automatic discovery of 100-miRNA signature for cancer classification using ensemble feature selection

A Lopez-Rincon, M Martinez-Archundia… - BMC …, 2019 - Springer
Background MicroRNAs (miRNAs) are noncoding RNA molecules heavily involved in
human tumors, in which few of them circulating the human body. Finding a tumor-associated …

Methylation deregulation of miRNA promoters identifies miR124-2 as a survival biomarker in Breast Cancer in very young women

SS Oltra, M Peña-Chilet, V Vidal-Tomas, K Flower… - Scientific reports, 2018 - nature.com
MiRNAs are part of the epigenetic machinery, and are also epigenetically modified by DNA
methylation. MiRNAs regulate expression of different genes, so any alteration in their …