BACKGROUND Successful treatment of breast cancer is enhanced by early detection and, if
possible, subsequent patient-tailored therapy. Toward this goal, it is essential to identify and …

MicroRNAs are small non-coding RNAs that participate in different biological processes,
providing subtle combinational regulation of cellular pathways, often by regulating …

The Pax7 transcription factor is required for muscle satellite cell biogenesis and specification
of the myogenic precursor lineage. Pax7 is expressed in proliferating myoblasts but is …

Background Several lines of evidence have suggested that estrogen receptor α (ERα)–
negative breast tumors, which are highly aggressive and nonresponsive to hormonal …

Amyotrophic lateral sclerosis (ALS) is a lethal motor neuron disease that progressively
debilitates neuronal cells that control voluntary muscle activity. Biomarkers are urgently …

MicroRNAs (miRNAs) are short, noncoding RNAs that generally base-pair within the 3′
untranslated region of target mRNAs causing translational inhibition and/or mRNA …

MicroRNAs (miRNAs) are single-stranded, non-coding, 19–25 nucleotide RNA molecules
that have been observed to be dysregulated in many diseases including cancer. miRNAs …

It is increasingly recognized that the mechanisms underlying ischemic cell death are
sexually dimorphic. Stroke-induced cell death in males is initiated by the mitochondrial …

Triple negative breast cancer (TNBC) is a type of aggressive breast cancer lacking the
expression of estrogen receptors (ER), progesterone receptors (PR) and human epidermal …

Aims MicroRNAs (miRNAs) are the targeting signal-transduction pathways that can mediate
tumorigenesis via their down and/or up-regulation. For example, miR-21 and miR-206 can …