Recent studies have shown that premature cellular senescence and normal organ
development and function depend on the type V intermediate filament proteins, the lamins …

Correlative microscopy is the application of two or more distinct microscopy techniques to
the same region of a sample, generating complementary morphological, structural and …

In animals, the nuclear lamina is a fibrillar meshwork on the inner surface of the nuclear
envelope, composed of coiled-coil lamin proteins and lamin binding membrane proteins …

Hutchinson-Gilford progeria syndrome (HGPS) is a human progeroid disease caused by a
point mutation on the LMNA gene. We reported previously that the accumulation of the …

The functions and morphology of cellular membranes are intimately related and depend not
only on their protein content but also on the repertoire of lipids that comprise them. In the …

The majority of known nuclear proteins are highly mobile. The molecular mechanisms by
which they accumulate inside stable compartments that are not separated from the …

Nuclear pore complexes (NPCs) are embedded in the nuclear envelope and built from∼ 30
different nucleoporins (Nups) in multiple copies, few are integral membrane proteins. One of …

Recent advances in fluorescence microscopy have opened up new possibilities to
investigate chromosomal and nuclear 3D organization on the nanoscale. We here discuss …

The technique of obtaining spherical particles from rod-like plant virus, tobacco mosaic virus,
in a preparative scale was developed. The conditions of tobacco mosaic virus isolation for …

The nuclear envelope (NE) is a fundamental structure of the nucleus and plays an important
role in nuclear morphology through the strict regulation of NE protein function. Beyond its …