The content and size of hyaluronan in biological fluids and tissues

MK Cowman, HG Lee, KL Schwertfeger… - Frontiers in …, 2015 - frontiersin.org
Hyaluronan is a simple repeating disaccharide polymer, synthesized at the cell surface by
integral membrane synthases. The repeating sequence is perfectly homogeneous, and is …

[PDF][PDF] Hyaluronan: preparation, structure, properties, and applications

L Lapcık Jr, L Lapcık, S De Smedt, J Demeester… - Chem …, 1998 - researchgate.net
Hyaluronan (HA, Figure 1), a high molecular weight biopolysaccharide, was discovered by
Meyer and Palmer in 1934 in the vitreous humor of cattle eyes. 1 HA is a member of a group …

Chemical and enzymatic fractionation of cell walls from Fucales: insights into the structure of the extracellular matrix of brown algae

E Deniaud-Bouët, N Kervarec, G Michel… - Annals of …, 2014 - academic.oup.com
Background and Aims Brown algae are photosynthetic multicellular marine organisms
evolutionarily distant from land plants, with a distinctive cell wall. They feature carbohydrates …

[图书][B] Electrophoresis in practice: a guide to methods and applications of DNA and protein separations

R Westermeier - 2016 - books.google.com
This fifth edition of the successful, long-selling classic has been completely revised and
expanded, omitting some topics on obsolete DNA electrophoresis, but now with a …

CD44 interaction with Na+-H+ exchanger (NHE1) creates acidic microenvironments leading to hyaluronidase-2 and cathepsin B activation and breast tumor cell …

LYW Bourguignon, PA Singleton, F Diedrich… - Journal of Biological …, 2004 - ASBMB
We have explored CD44 (a hyaluronan (HA) receptor) interaction with a Na+-H+ exchanger
(NHE1) and hyaluronidase-2 (Hyal-2) during HA-induced cellular signaling in human breast …

A recombinant human enzyme for enhanced interstitial transport of therapeutics

LH Bookbinder, A Hofer, MF Haller, ML Zepeda… - Journal of Controlled …, 2006 - Elsevier
Subcutaneously injected therapeutics must pass through the interstitial matrix of the skin in
order to reach their intended targets. This complex, three-dimensional structure limits the …

A multi-stimuli responsive gold nanocage–hyaluronic platform for targeted photothermal and chemotherapy

Z Wang, Z Chen, Z Liu, P Shi, K Dong, E Ju, J Ren… - Biomaterials, 2014 - Elsevier
Noninvasive and pinpointed intracellular drug release that responds to multiple stimulus is
still a formidable challenge for cancer therapy. Herein, we reported a multi-stimuli …

Glycosaminoglycans detection methods: Applications of mass spectrometry

F Kubaski, H Osago, RW Mason, S Yamaguchi… - Molecular genetics and …, 2017 - Elsevier
Glycosaminoglycans (GAGs) are long blocks of negatively charged polysaccharides. They
are one of the major components of the extracellular matrix and play multiple roles in …

Recognition of bacterial capsular polysaccharides and lipopolysaccharides by the macrophage mannose receptor

S Zamze, L Martinez-Pomares, H Jones… - Journal of Biological …, 2002 - ASBMB
The in vitro binding of the macrophage mannose receptor to a range of different bacterial
polysaccharides was investigated. The receptor was shown to bind to purified capsular …

Fucoidans and fucoidanases—focus on techniques for molecular structure elucidation and modification of marine polysaccharides

AD Holtkamp, S Kelly, R Ulber, S Lang - Applied microbiology and …, 2009 - Springer
The research field of fucoidans (sulphated polysaccharides from algae) and fucoidanases
was strongly developing in recent years. Several different fucoidans and a few fucoidan …