Oxidative stress is a component of many diseases, including atherosclerosis, chronic
obstructive pulmonary disease, Alzheimer disease and cancer. Although numerous small …

The reactive oxygen species (ROS)-producing enzyme NADPH oxidase (NOX) was first
identified in the membrane of phagocytic cells. For many years, its only known role was in …

Reactive oxygen species (ROS) are fundamental for macrophages to eliminate invasive
microorganisms. However, as observed in nonphagocytic cells, ROS play essential roles in …

Oxidative stress, a cytopathic outcome of excessive generation of ROS and the repression of
antioxidant defense system for ROS elimination, is involved in the pathogenesis of multiple …

Interventional coronary reperfusion strategies are widely adopted to treat acute myocardial
infarction, but morbidity and mortality of acute myocardial infarction are still high …

Simple Summary Ferroptosis is a type of cell death, which is morphologically and
mechanistically distinct from other type of cell death pathways such as apoptosis and …

Cancer is characterized by increased oxidative stress, an imbalance between reactive
oxygen species (ROS) and antioxidants. Enhanced ROS accumulation, as a result of …

Ebselen is an organoselenium compound exhibiting hydroperoxide-and peroxynitrite-
reducing activity, acting as a glutathione peroxidase and peroxiredoxin enzyme mimetic …

Reactive oxygen species (ROS) are pervasive signaling molecules in biological systems. In
humans, a lack of ROS causes chronic and extreme bacterial infections, while uncontrolled …

NADPH oxidases (NOXs) are transmembrane enzymes that are devoted to the production of
reactive oxygen species (ROS). In cancers, dysregulation of NOX enzymes affects ROS …