Mechanism of antimicrobial peptides: antimicrobial, anti-inflammatory and antibiofilm activities

Y Luo, Y Song - International journal of molecular sciences, 2021 - mdpi.com
Antimicrobial peptides (AMPs) are regarded as a new generation of antibiotics. Besides
antimicrobial activity, AMPs also have antibiofilm, immune-regulatory, and other activities …

Intracellular targeting mechanisms by antimicrobial peptides

CF Le, CM Fang, SD Sekaran - Antimicrobial agents and …, 2017 - Am Soc Microbiol
Antimicrobial peptides (AMPs) are expressed in various living organisms as first-line host
defenses against potential harmful encounters in their surroundings. AMPs are short …

Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria?

KA Brogden - Nature reviews microbiology, 2005 - nature.com
Antimicrobial peptides are an abundant and diverse group of molecules that are produced
by many tissues and cell types in a variety of invertebrate, plant and animal species. Their …

Antimicrobial peptides and macromolecules for combating microbial infections: from agents to interfaces

L Yu, K Li, J Zhang, H Jin, A Saleem… - ACS Applied Bio …, 2022 - ACS Publications
Bacterial resistance caused by the overuse of antibiotics and the shelter of biofilms has
evolved into a global health crisis, which drives researchers to continuously explore …

[HTML][HTML] Mechanism of the binding, insertion and destabilization of phospholipid bilayer membranes by α-helical antimicrobial and cell non-selective membrane-lytic …

Y Shai - Biochimica et Biophysica Acta (BBA)-Biomembranes, 1999 - Elsevier
Permeation of the cell membrane leading to cell death is a mechanism used by a large
number of membrane-lytic peptides. Some are linear, mostly helical, and others contain one …

Mode of action of membrane active antimicrobial peptides

Y Shai - Peptide Science: Original Research on Biomolecules, 2002 - Wiley Online Library
Water‐membrane soluble protein and peptide toxins are used in the defense and offense
systems of all organisms, including plants and humans. A major group includes …

Antimicrobial peptides: linking partition, activity and high membrane-bound concentrations

MN Melo, R Ferre, MARB Castanho - Nature Reviews Microbiology, 2009 - nature.com
An increasing amount of information on the action of antimicrobial peptides (AMPs) at the
molecular level has not yet been translated into a comprehensive understanding of effects in …

Mode of action of linear amphipathic α‐helical antimicrobial peptides

Z Oren, Y Shai - Peptide Science, 1998 - Wiley Online Library
The increasing resistance of bacteria to conventional antibiotics resulted in a strong effort to
develop antimicrobial compounds with new mechanisms of action. Antimicrobial peptides …

[HTML][HTML] Why and how are peptide–lipid interactions utilized for self-defense? Magainins and tachyplesins as archetypes

K Matsuzaki - Biochimica et Biophysica Acta (BBA)-Biomembranes, 1999 - Elsevier
Animals as well as plants defend themselves against invading pathogenic microorganisms
utilizing cationic antimicrobial peptides, which rapidly kill various microbes without exerting …

Design of antimicrobial polymers

P Pham, S Oliver, C Boyer - Macromolecular Chemistry and …, 2023 - Wiley Online Library
Antibiotic resistance has become a critical issue, alarming the healthcare and agriculture
sectors worldwide. Thanks to rapid advancements in polymer science, antimicrobial …