Regulation and function of autophagy in pancreatic cancer

J Li, X Chen, R Kang, H Zeh, DJ Klionsky, D Tang - Autophagy, 2021 - Taylor & Francis
Oncogenic KRAS mutation-driven pancreatic ductal adenocarcinoma is currently the fourth-
leading cause of cancer-related deaths in the United States. Macroautophagy (hereafter …

[HTML][HTML] A bioinformatics analysis, pre-clinical and clinical conception of autophagy in pancreatic cancer: complexity and simplicity in crosstalk

M Ashrafizadeh, W Zhang, R Zou, G Sethi… - Pharmacological …, 2023 - Elsevier
Pancreatic cancer (PC) is a serious gastrointestinal tract disease for which the 5-year
survival rate is less than 10%, even in developed countries such as the USA. The genomic …

A Sonication‐Activated Valence‐Variable Sono‐Sensitizer/Catalyst for Autography Inhibition/Ferroptosis‐Induced Tumor Nanotherapy

W Feng, Z Liu, L Xia, M Chen, X Dai… - Angewandte Chemie …, 2022 - Wiley Online Library
The effective deployment of reactive oxygen species (ROS)‐mediated oncotherapy in
practice remains challenging, mired by uncontrollable catalytic processes, stern reaction …

The role of autophagy in pancreatic cancer—Recent advances

M New, S Tooze - Biology, 2019 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest cancers with a 5-
year survival rate of only 9%, despite ongoing efforts to improve treatment. This dismal …

Tumor Cell Derived Lnc‐FSD2‐31: 1 Contributes to Cancer‐Associated Fibroblasts Activation in Pancreatic Ductal Adenocarcinoma Progression through Extracellular …

X Geng, L Li, Y Luo, W Yang, J Hu, Z Zhao… - Advanced …, 2023 - Wiley Online Library
Pancreatic ductal adenocarcinoma (PDAC) presents with high mortality and short overall
survival. Cancer‐associated fibroblasts (CAFs) act as refuge for cancer cells in PDAC …

Lnc-PFAR facilitates autophagy and exacerbates pancreatic fibrosis by reducing pre-miR-141 maturation in chronic pancreatitis

T Zhang, G Zhang, W Yang, H Chen, J Hu, Z Zhao… - Cell Death & …, 2021 - nature.com
Chronic pancreatitis (CP) is described as progressive inflammatory fibrosis of pancreas,
accompanied with irreversible impaired endocrine and exocrine insufficiency. Pancreatic …

USP1 regulates TAZ protein stability through ubiquitin modifications in breast cancer

A Mussell, H Shen, Y Chen, M Mastri, KH Eng… - Cancers, 2020 - mdpi.com
Simple Summary Triple-Negative breast cancer (TNBC) is the most aggressive form of
breast cancer in women. Targeted therapies for the treatment of this disease are severely …

Notch signaling induces either apoptosis or cell fate change in multiciliated cells during mucociliary tissue remodeling

A Tasca, M Helmstädter, MM Brislinger, M Haas… - Developmental cell, 2021 - cell.com
Multiciliated cells (MCCs) are extremely highly differentiated, presenting> 100 cilia and
basal bodies. Therefore, MCC fate is thought to be terminal and irreversible. We analyzed …

CTRP3 alleviates myocardial ischemia/reperfusion injury in mice through activating LAMP1/JIP2/JNK pathway

Y Song, Y Zhang, Z Wan, J Pan, F Gao, F Li… - International …, 2022 - Elsevier
Myocardial ischemia reperfusion (I/R) injury is an important complication of myocardial
infarction reperfusion therapy, and no effective treatment has been identified. Based on …

Metabarcoding Reveals Temporal Patterns of Community Composition and Realized Thermal Niches of Thalassiosira Spp. (Bacillariophyceae) from the Narragansett …

TA Rynearson, SA Flickinger, DN Fontaine - Biology, 2020 - mdpi.com
Diatoms generate nearly half of marine primary production and are comprised of a diverse
array of species that are often morphologically cryptic or difficult to identify using light …