Antibacterial resistance is one of the greatest threats to human health. The development of
new therapeutics against bacterial pathogens has slowed drastically since the approvals of …

Antimicrobial resistance is one of the major problems in current practical medicine. The
spread of genes coding for resistance determinants among bacteria challenges the use of …

The genus Enterobacter is a member of the ESKAPE group, which contains the major
resistant bacterial pathogens. First described in 1960, this group member has proven to be …

Despite tremendous successes in the field of antibiotic discovery seen in the previous
century, infectious diseases have remained a leading cause of death. More specifically …

Gram-negative bacteria and their complex cell envelope, which comprises an outer
membrane and an inner membrane, are an important and attractive system for studying the …

The recent outbreaks of infectious diseases caused by multidrug-resistant pathogens have
sounded a piercing alarm for the need of new effective antimicrobial agents to guard public …

This chapter analyzes the epidemiology of Carbapenem-Resistant Enterobacteriaceae
(CRE) as well as current and future treatment options against the increasingly resistant …

Bacteria have evolved a wide range of mechanisms to harm and kill their competitors,
including chemical, mechanical and biological weapons. Here we review the incredible …

Rising antibiotic resistance is a global threat that is projected to cause more deaths than all
cancers combined by 2050. In this review, we set to summarize the current state of antibiotic …

The antimicrobial resistance crisis is a global health issue requiring discovery and
development of novel therapeutics. However, conventional screening of natural products or …