Randall's plaque and calcium oxalate stone formation: role for immunity and inflammation

SR Khan, BK Canales… - Nature Reviews …, 2021 - nature.com
Idiopathic calcium oxalate (CaOx) stones often develop attached to Randall's plaque
present on kidney papillary surfaces. Similar to the plaques formed during vascular …

Recent advances on the mechanisms of kidney stone formation

Z Wang, Y Zhang, J Zhang… - … journal of molecular …, 2021 - spandidos-publications.com
Kidney stone disease is one of the oldest diseases known to medicine; however, the
mechanisms of stone formation and development remain largely unclear. Over the past …

The genetics of kidney stone disease and nephrocalcinosis

P Singh, PC Harris, DJ Sas, JC Lieske - Nature Reviews Nephrology, 2022 - nature.com
Kidney stones (also known as urinary stones or nephrolithiasis) are highly prevalent,
affecting approximately 10% of adults worldwide, and the incidence of stone disease is …

[HTML][HTML] Global trends in incidence and burden of urolithiasis from 1990 to 2019: an analysis of global burden of disease study data

J Lang, A Narendrula, A El-Zawahry… - European urology open …, 2022 - Elsevier
Background Urolithiasis is among the most common urologic diagnoses globally, with
substantial burden and cost on healthcare systems worldwide. Increasing evidence links …

Roles for exosome in various kidney diseases and disorders

V Thongboonkerd - Frontiers in pharmacology, 2020 - frontiersin.org
Exosome is a nanoscale vesicle with a size range of 30–100 nm. It is secreted from cell to
extracellular space by exocytosis after fusion of multivesicular body (MVB)(formed by …

A multidisciplinary consensus on dehydration: definitions, diagnostic methods and clinical implications

J Lacey, J Corbett, L Forni, L Hooper, F Hughes… - Annals of …, 2019 - Taylor & Francis
Background: Dehydration appears prevalent, costly and associated with adverse outcomes.
We sought to generate consensus on such key issues and elucidate need for further …

Drosophila melanogaster: a simple genetic model of kidney structure, function and disease

JAT Dow, M Simons, MF Romero - Nature Reviews Nephrology, 2022 - nature.com
Although the genetic basis of many kidney diseases is being rapidly elucidated, their
experimental study remains problematic owing to the lack of suitable models. The fruitfly …

Prevalence and trends of urolithiasis among adults

M Abufaraj, J Al Karmi, L Yang - Current Opinion in Urology, 2022 - journals.lww.com
Prevalence and trends of urolithiasis among adults : Current Opinion in Urology Prevalence
and trends of urolithiasis among adults : Current Opinion in Urology Log in or Register …

Role of ROS-induced NLRP3 inflammasome activation in the formation of calcium oxalate nephrolithiasis

Y Liu, Y Sun, J Kang, Z He, Q Liu, J Wu, D Li… - Frontiers in …, 2022 - frontiersin.org
Calcium oxalate nephrolithiasis is a common and highly recurrent disease in urology;
however, its precise pathogenesis is still unknown. Recent research has shown that renal …

Vitamin D, hypercalciuria and kidney stones

E Letavernier, M Daudon - Nutrients, 2018 - mdpi.com
The estimated lifetime risk of nephrolithiasis is growing nowadays, and the formation of
kidney stones is frequently promoted by hypercalciuria. Vitamin D, and especially its active …