[HTML][HTML] Lipoproteins and lipids in cardiovascular disease: from mechanistic insights to therapeutic targeting
J Soppert, M Lehrke, N Marx, J Jankowski… - Advanced drug delivery …, 2020 - Elsevier
With cardiovascular disease being the leading cause of morbidity and mortality worldwide,
effective and cost-efficient therapies to reduce cardiovascular risk are highly needed. Lipids …
effective and cost-efficient therapies to reduce cardiovascular risk are highly needed. Lipids …
Obesity and osteoarthritis, more than just wear and tear: pivotal roles for inflamed adipose tissue and dyslipidaemia in obesity-induced osteoarthritis
E Thijssen, A Van Caam, PM Van Der Kraan - Rheumatology, 2015 - academic.oup.com
OA is a degenerative joint disease characterized by articular cartilage degradation,
osteophyte formation, synovitis, and subchondral bone sclerosis. One of OAs main risk …
osteophyte formation, synovitis, and subchondral bone sclerosis. One of OAs main risk …
HDL and cardiovascular disease: atherogenic and atheroprotective mechanisms
The lipoprotein HDL has two important roles: first, it promotes reverse cholesterol transport,
and second, it modulates inflammation. Epidemiological studies show that HDL-cholesterol …
and second, it modulates inflammation. Epidemiological studies show that HDL-cholesterol …
[PDF][PDF] Structure of HDL: particle subclasses and molecular components
A Kontush, M Lindahl, M Lhomme… - High Density …, 2015 - library.oapen.org
A molecular understanding of high-density lipoprotein (HDL) will allow a more complete
grasp of its interactions with key plasma remodelling factors and with cell-surface proteins …
grasp of its interactions with key plasma remodelling factors and with cell-surface proteins …
An abundant dysfunctional apolipoprotein A1 in human atheroma
Y Huang, JA DiDonato, BS Levison, D Schmitt, L Li… - Nature medicine, 2014 - nature.com
Recent studies have indicated that high-density lipoproteins (HDLs) and their major
structural protein, apolipoprotein A1 (apoA1), recovered from human atheroma are …
structural protein, apolipoprotein A1 (apoA1), recovered from human atheroma are …
High-density lipoprotein function, dysfunction, and reverse cholesterol transport
Although high high-density lipoprotein (HDL)-cholesterol levels are associated with
decreased cardiovascular risk in epidemiological studies, recent genetic and …
decreased cardiovascular risk in epidemiological studies, recent genetic and …
Protein carbamylation links inflammation, smoking, uremia and atherogenesis
Post-translational modification and functional impairment of proteins through carbamylation
is thought to promote vascular dysfunction during end-stage renal disease. Cyanate, a …
is thought to promote vascular dysfunction during end-stage renal disease. Cyanate, a …
The role and function of HDL in patients with diabetes mellitus and the related cardiovascular risk
M Femlak, A Gluba-Brzózka… - Lipids in health and …, 2017 - Springer
Background Diabetes mellitus (DM) is a major public health problem which prevalence is
constantly raising, particularly in low-and middle-income countries. Both diabetes mellitus …
constantly raising, particularly in low-and middle-income countries. Both diabetes mellitus …
Myeloperoxidase, paraoxonase-1, and HDL form a functional ternary complex
Y Huang, Z Wu, M Riwanto, S Gao… - The Journal of …, 2013 - Am Soc Clin Investig
Myeloperoxidase (MPO) and paraoxonase 1 (PON1) are high-density lipoprotein–
associated (HDL-associated) proteins mechanistically linked to inflammation, oxidant stress …
associated (HDL-associated) proteins mechanistically linked to inflammation, oxidant stress …
Cryo-EM structure of the ribosome–SecYE complex in the membrane environment
Abstract The ubiquitous SecY–Sec61 complex translocates nascent secretory proteins
across cellular membranes and integrates membrane proteins into lipid bilayers. Several …
across cellular membranes and integrates membrane proteins into lipid bilayers. Several …