Inertial microfluidics: current status, challenges, and future opportunities

N Xiang, Z Ni - Lab on a Chip, 2022 - pubs.rsc.org
Inertial microfluidics uses the hydrodynamic effects induced at finite Reynolds numbers to
achieve passive manipulation of particles, cells, or fluids and offers the advantages of high …

Label-free isolation of exosomes using microfluidic technologies

S Hassanpour Tamrin, A Sanati Nezhad, A Sen - ACS nano, 2021 - ACS Publications
Exosomes are cell-derived structures packaged with lipids, proteins, and nucleic acids. They
exist in diverse bodily fluids and are involved in physiological and pathological processes …

Advances in microfluidics: technical innovations and applications in diagnostics and therapeutics

G Aubry, HJ Lee, H Lu - Analytical Chemistry, 2023 - ACS Publications
Microfluidics describes the study of systems that operate fluids at miniature scales, often in
microchannels. It is powerful in scaling down biological experiments by many orders of …

Multiphysics microfluidics for cell manipulation and separation: a review

H Cha, H Fallahi, Y Dai, D Yuan, H An, NT Nguyen… - Lab on a Chip, 2022 - pubs.rsc.org
Multiphysics microfluidics, which combines multiple functional physical processes in a
microfluidics platform, is an emerging research area that has attracted increasing interest for …

Advances in technical assessment of spiral inertial microfluidic devices toward bioparticle separation and profiling: A critical review

M Bagi, F Amjad, SM Ghoreishian… - BioChip Journal, 2024 - Springer
Separation of micro-and nano-sized bioparticles is essential for efficient diagnostics,
chemical and biological analyses, drug development, food and chemical processing, and …

Tuning particle inertial separation in sinusoidal channels by embedding periodic obstacle microstructures

H Cha, H Fallahi, Y Dai, S Yadav, S Hettiarachchi… - Lab on a Chip, 2022 - pubs.rsc.org
Inertial microfluidics functions solely based on the fluid dynamics at relatively high flow
speed. Thus, channel geometry is the critical design parameter that contributes to the …

Recent progress of inertial microfluidic-based cell separation

X Xu, X Huang, J Sun, R Wang, J Yao, W Han, M Wei… - Analyst, 2021 - pubs.rsc.org
Cell separation has consistently been a pivotal technology of sample preparation in
biomedical research. Compared with conventional bulky cell separation technologies …

Advances in microfluidics for single red blood cell analysis

GV Grigorev, AV Lebedev, X Wang, X Qian… - Biosensors, 2023 - mdpi.com
The utilizations of microfluidic chips for single RBC (red blood cell) studies have attracted
great interests in recent years to filter, trap, analyze, and release single erythrocytes for …

Multi-dimensional-double-spiral (MDDS) inertial microfluidic platform for sperm isolation directly from the raw semen sample

H Jeon, C Cremers, D Le, J Abell, J Han - Scientific reports, 2022 - nature.com
Here, we propose a fully-automated platform using a spiral inertial microfluidic device for
standardized semen preparation that can process patient-derived semen samples with …

[HTML][HTML] 3D-stacked multistage inertial microfluidic chip for high-throughput enrichment of circulating tumor cells

X Xu, X Huang, J Sun, J Chen, G Wu, Y Yao… - Cyborg and Bionic …, 2022 - spj.science.org
Whether for cancer diagnosis or single-cell analysis, it remains a major challenge to isolate
the target sample cells from a large background cell for high-efficiency downstream …