Scavenger receptors were originally identified by their ability to recognize and to remove
modified lipoproteins; however, it is now appreciated that they carry out a striking range of …

Blood platelets have long been recognised to bring about primary haemostasis with
deficiencies in platelet production and function manifesting in bleeding while upregulated …

Background—Visceral fat is a key regulator site for the process of inflammation, and
atherosclerotic lesions are essentially an inflammatory response. Methods and Results …

▪ Abstract Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in
the Western world. Its incidence has also been increasing lately in developing countries …

The endothelium plays a key role in vascular homeostasis through the release of a variety of
autocrine and paracrine substances (1). In addition to vasodilation, a healthy endothelium is …

The adhesion molecule P-selectin (CD62P) is of interest because of its role in modulating
interactions between blood cells and the endothelium, and also because of the possible use …

von Willebrand factor (VWF) plays a pivotal role in platelet adhesion and aggregation at
sites of high shear rates (eg, in coronary arteries that have stenotic or ruptured …

Background—P-selectin, a cell-surface adhesion molecule involved in leukocyte rolling and
attachment, has been hypothesized to play a role in the initiation of atherosclerosis …

Dyslipidemia is associated with a prothrombotic phenotype; however, the mechanisms
responsible for enhanced platelet reactivity remain unclear. Proatherosclerotic lipid …

Over the past decade, the platelet has emerged as a pivotal entity in cardiovascular
diseases. Indeed, the'preeminence of the platelet'has spawned a variety of drugs that have …