This review is focused on purinergic neurotransmission, ie, ATP released from nerves as a
transmitter or cotransmitter to act as an extracellular signaling molecule on both pre-and …

P2X7 receptors are ligand-gated ion channels, expressed as homo-oligomeric assemblies
of individual subunits. They are widely distributed at immunocompetent cells of the central …

The size and shape of dendritic arbors are prime determinants of neuronal connectivity and
function. We asked how ON-OFF direction-selective ganglion cells (ooDSGCs) in mouse …

We consider the impact of purinergic signaling on the physiology of the special senses of
vision, smell, taste and hearing. Purines (particularly ATP and adenosine) act as …

Adenosine triphosphate (ATP), an energy source currency in cells, is released or leaked to
the extracellular space under both physiological and pathological conditions. Extracellular …

Azobenzene photoswitches confer light sensitivity onto retinal ganglion cells (RGCs) in blind
mice, making these compounds promising candidates as vision-restoring drugs in humans …

Vesicular nucleotide transporter (VNUT) is required for active accumulation of adenosine tri-
phosphate (ATP) into vesicles for purinergic neurotransmission, however, the cell types that …

Retinal injuries and diseases are major causes of human disability involving vision
impairment by the progressive and permanent loss of retinal neurons. During development …

The retina contains two populations of cholinergic amacrine cells, one positioned in the
ganglion cell layer (GCL) and the other in the inner nuclear layer (INL), that together …

Many developing neural circuits generate synchronized bursting activity among neighboring
neurons, a pattern thought to be important for sculpting precise neural connectivity. Network …