Understanding microRNAs in the context of infection to find new treatments against human bacterial pathogens

Á Mourenza, B Lorente-Torres, E Durante… - Antibiotics, 2022 - mdpi.com
The development of RNA-based anti-infectives has gained interest with the successful
application of mRNA-based vaccines. Small RNAs are molecules of RNA of< 200 …

The critical role of miRNA in bacterial zoonosis

S Chen, Z Lei, T Sun - International Immunopharmacology, 2024 - Elsevier
The public's health and the financial sustainability of international societies remain
threatened by bacterial zoonoses, with limited reliable diagnostic and therapeutic options …

Study of microRNA expression in Salmonella Typhimurium-infected porcine ileum reveals miR-194a-5p as an important regulator of the TLR4-mediated inflammatory …

J Herrera-Uribe, S Zaldívar-López, C Aguilar… - Veterinary …, 2022 - Springer
Abstract Infection with Salmonella Typhimurium (S. Typhimurium) is a common cause of
food-borne zoonosis leading to acute gastroenteritis in humans and pigs, causing economic …

Computational prediction and experimental validation of Salmonella Typhimurium SopE-mediated fine-tuning of autophagy in intestinal epithelial cells

A Demeter, AC Jacomin, L Gul, A Lister… - Frontiers in Cellular …, 2022 - frontiersin.org
Macroautophagy is a ubiquitous homeostasis and health-promoting recycling process of
eukaryotic cells, targeting misfolded proteins, damaged organelles and intracellular …

Non-coding RNA Networks in Infection

H Janga, N Schmerer, M Aznaourova… - Computational Biology of …, 2024 - Springer
In the face of global health challenges posed by infectious diseases and the emergence of
drug-resistant pathogens, the exploration of cellular non-coding RNA (ncRNA) networks has …

Role of microRNAs in immunoregulatory functions of epithelial cells

N Jafari, S Abediankenari - BMC immunology, 2024 - Springer
Epithelial cells (ECs) provide the first line of defense against microbial threats and
environmental challenges. They participate in the host's immune responses via the …

E2F transcription factor 1 elevates cyclin D1 expression by suppressing transcription of microRNA‐107 to augment progression of glioma

H Xie, S Lv, Z Wang, X Yuan - Brain and Behavior, 2021 - Wiley Online Library
Background Dysregulation of microRNAs has been frequently implicated in the progression
of human diseases, including glioma. This study aims to explore the interaction between …

5'isomiR-183-5p|+ 2 elicits tumor suppressor activity in a negative feedback loop with E2F1

X Li, BE Michels, OE Tosun, J Jung, J Kappes… - Journal of Experimental …, 2022 - Springer
Abstract Background MicroRNAs (miRNAs) and isomiRs play important roles in
tumorigenesis as essential regulators of gene expression. 5'isomiRs exhibit a shifted seed …

Peran HMGB1 dalam Infeksi Sel

HH Idrus - 2024 - repository.penerbiteureka.com
HMGB1, singkatan dari High Mobility Group Box 1, adalah protein yang memiliki peran
penting dalam regulasi respons imun dan inflamasi, terutama dalam konteks infeksi sel …

The Role of Er Stress in the Immune Response to Enteric Bacterial Infections

LA Sweet - 2022 - search.proquest.com
Abstract Citrobacter rodentium and Salmonella Typhimurium are enteric bacterial pathogens
that are spread through the fecal to oral route and lead to the induction of inflammation and …