Introduction: Fifty-three years after the first description of an inherited prothrombotic
condition (antithrombin deficiency), our knowledge on hereditary and acquired causes of …

Introduction Venous thromboembolism (VTE) is a complex disease that aggregates in
families. Both acquired and genetic risk factors are important. Proper recognition and …

Venous thromboembolism (VTE) has important heritable components. In the past 20 years,
knowledge in this field has greatly increased with the identification of a number of gene …

Venous thrombosis (VT) is a common multifactorial disease with a genetic component that
was first suspected nearly 60 years ago. In this review, we document the genetic …

Snake venoms have evolved primarily to immobilize and kill prey, and consequently, they
contain some of the most potent natural toxins. Part of that armory is a range of hemotoxic …

High coagulation factor VIII (FVIII) levels comprise a common risk factor for venous
thromboembolism (VTE), but the underlying genetic determinants are largely unknown. We …

Introduction: The discovery of the factor V Leiden (FVL) missense mutation (Arg506Gln)
causing factor V resistance to the anticoagulant action of activated protein C was a landmark …

Venous thromboembolism (VTE) has a strong genetic component. This review summarizes
what is known at the seventeen genes that are now well established to harbour VTE …

Objective—Two different prothrombin variants, p. Arg596Leu and p. Arg596Gln, conferring
antithrombin resistance to patients with venous thromboembolism have been recently …

Vitamin K-dependent clotting factors are commonly divided into prohemorrhagic (FII, FVII,
FIX, and FX) and antithrombotic (protein C and protein S). Furthermore, another protein …