Adult stem cells ensure tissue homeostasis and regeneration after injury. Due to their
longevity and functional requirements, throughout their life stem cells are subject to a …

Neurodevelopmental disorders (NDDs) are a heterogeneous and highly prevalent group of
psychiatric conditions marked by impairments in the nervous system. Their onset occurs …

Neurological disorders, including neurodegenerative diseases, are collectively a major
cause of death and disability worldwide. Whilst the underlying disease mechanisms remain …

During vertebrate development, embryonic cells pass through a continuum of transitory
pluripotent states that precede multi-lineage commitment and morphogenesis. Such states …

This review explores the application of induced pluripotent stem cells (iPSCs) in
regenerative medicine. The therapeutic significance of iPSC-derived cell therapy within …

Reporter alleles are essential for advancing research with human induced pluripotent stem
cells (hiPSCs), notably in developmental biology and disease modeling. This study …

Rotator cuff tears (RCT) are the most common cause of shoulder pain among adults.“Rotator
cuff” refers to the four muscles that cover the shoulder joint: supraspinatus, infraspinatus …

Abstract Assay for Transposase-Accessible Chromatin with sequencing (ATAC-seq) reveals
chromatin accessibility across the genome. Currently, no method specifically detects …

Generation of induced pluripotent stem cells (iPSCs) is inefficient and stochastic. The
underlying causes for these deficiencies are elusive. Here, we showed that the …

The position of the nucleosome and chromatin packaging in eukaryotic genomes govern
gene regulation and cellular functions. Assay for Transposase-Accessible Chromatin using …