Aspergillus fumigatus and Aspergillosis in 2019

JP Latgé, G Chamilos - Clinical microbiology reviews, 2019 - Am Soc Microbiol
Aspergillus fumigatus is a saprotrophic fungus; its primary habitat is the soil. In its ecological
niche, the fungus has learned how to adapt and proliferate in hostile environments. This …

Plant cell wall–degrading enzymes and their secretion in plant-pathogenic fungi

CP Kubicek, TL Starr, NL Glass - Annual review of …, 2014 - annualreviews.org
Approximately a tenth of all described fungal species can cause diseases in plants. A
common feature of this process is the necessity to pass through the plant cell wall, an …

Luteolin alleviates cognitive impairment in Alzheimer's disease mouse model via inhibiting endoplasmic reticulum stress-dependent neuroinflammation

J Kou, J Shi, Y He, J Hao, H Zhang, D Luo… - Acta Pharmacologica …, 2022 - nature.com
Luteolin is a flavonoid in a variety of fruits, vegetables, and herbs, which has shown anti-
inflammatory, antioxidant, and anti-cancer neuroprotective activities. In this study, we …

Pathogenesis of Aspergillus fumigatus in Invasive Aspergillosis

TRT Dagenais, NP Keller - Clinical microbiology reviews, 2009 - Am Soc Microbiol
Aspergillus species are globally ubiquitous saprophytes found in a variety of ecological
niches. Almost 200 species of aspergilli have been identified, less than 20 of which are …

Immunity to fungal infections

L Romani - Nature Reviews Immunology, 2011 - nature.com
Fungal diseases represent an important paradigm in immunology, as they can result from
either a lack of recognition by the immune system or overactivation of the inflammatory …

Regulatory circuitry governing fungal development, drug resistance, and disease

RS Shapiro, N Robbins, LE Cowen - Microbiology and molecular …, 2011 - Am Soc Microbiol
Pathogenic fungi have become a leading cause of human mortality due to the increasing
frequency of fungal infections in immunocompromised populations and the limited …

Recognition of DHN-melanin by a C-type lectin receptor is required for immunity to Aspergillus

MHT Stappers, AE Clark, V Aimanianda, S Bidula… - Nature, 2018 - nature.com
Resistance to infection is critically dependent on the ability of pattern recognition receptors
to recognize microbial invasion and induce protective immune responses. One such family …

The genomes of three uneven siblings: footprints of the lifestyles of three Trichoderma species

M Schmoll, C Dattenböck… - Microbiology and …, 2016 - Am Soc Microbiol
The genus Trichoderma contains fungi with high relevance for humans, with applications in
enzyme production for plant cell wall degradation and use in biocontrol. Here, we provide a …

Cryptococcus extracellular vesicles properties and their use as vaccine platforms

J Rizzo, SSW Wong, AD Gazi… - Journal of …, 2021 - Wiley Online Library
Whereas extracellular vesicle (EV) research has become commonplace in different
biomedical fields, this field of research is still in its infancy in mycology. Here we provide a …

Discovery of a hapE Mutation That Causes Azole Resistance in Aspergillus fumigatus through Whole Genome Sequencing and Sexual Crossing

SMT Camps, BE Dutilh, MC Arendrup, AJMM Rijs… - PLoS …, 2012 - journals.plos.org
Azole compounds are the primary therapy for patients with diseases caused by Aspergillus
fumigatus. However, prolonged treatment may cause resistance to develop, which is …