Voltage-gated calcium channels are the primary mediators of depolarization-induced
calcium entry into neurons. There is great diversity of calcium channel subtypes due to …

The L-type Cav1. 2 calcium channel is present throughout the animal kingdom and is
essential for some aspects of CNS function, cardiac and smooth muscle contractility …

Calcium regulates a wide spectrum of physiological processes such as heartbeat, muscle
contraction, neuronal communication, hormone release, cell division, and gene …

Voltage-gated calcium channels are important mediators of several physiological processes,
including neuronal excitability and muscle contraction. At the molecular level, the channels …

The electrical characteristics of many neurons are remarkably robust in the face of changing
internal and external conditions. At the same time, neurons can be highly sensitive to …

Calcium channel β subunits have marked effects on the trafficking and on several of the
biophysical properties of all high voltage activated calcium channels. In this article I shall …

Migratory dendritic cells (migDCs) continuously patrol tissues and are activated by injury
and inflammation. Extracellular adenosine triphosphate (ATP) is released by damaged cells …

Voltage-activated calcium channels regulate the intracellular calcium concentration and
contribute thereby to calcium signalling in numerous cell types. These channels are widely …

Until recently we held the simple view that voltage-gated calcium channels consisted of an
α1 subunit, usually associated with auxiliary β subunits and α2δ subunits and that skeletal …

The voltage-gated Ca2+ channel β subunit (Cavβ) is a cytosolic auxiliary subunit that plays
an essential role in regulating the surface expression and gating properties of high-voltage …