Xpert MTB/RIF Ultra assay for tuberculosis disease and rifampicin resistance in children

AW Kay, T Ness, SE Verkuijl, K Viney… - Cochrane Database …, 2022 - cochranelibrary.com
Background Every year, an estimated one million children and young adolescents become
ill with tuberculosis, and around 226,000 of those children die. Xpert MTB/RIF Ultra (Xpert …

Xpert MTB/RIF and Xpert MTB/RIF Ultra assays for active tuberculosis and rifampicin resistance in children

AW Kay, LG Fernández, Y Takwoingi… - Cochrane Database …, 2020 - cochranelibrary.com
Background Every year, at least one million children become ill with tuberculosis and
around 200,000 children die. Xpert MTB/RIF and Xpert Ultra are World Health Organization …

Xpert Ultra stool testing to diagnose tuberculosis in children in Ethiopia and Indonesia: a model-based cost-effectiveness analysis

N Mafirakureva, E Klinkenberg, I Spruijt, J Levy… - BMJ open, 2022 - bmjopen.bmj.com
Objectives The WHO currently recommends stool testing using GeneXpert MTB/Rif (Xpert)
for the diagnosis of paediatric tuberculosis (TB). The simple one-step (SOS) stool method …

Exploring the impact of the COVID-19 pandemic on tuberculosis care and prevention

S Sahu, E Wandwalo… - Journal of the Pediatric …, 2022 - academic.oup.com
The COVID-19 pandemic has set back the global tuberculosis (TB) response by several
years. In 2020, access to TB prevention and care declined sharply, with TB notifications …

Treatment outcomes of children and adolescents receiving drug-resistant TB treatment in a routine TB programme, Mumbai, India

S Dhakulkar, M Das, N Sutar, V Oswal, D Shah… - PLoS …, 2021 - journals.plos.org
Background Childhood and adolescent drug-resistant TB (DR-TB) is one of the neglected
infectious diseases. Limited evidence exists around programmatic outcomes of children and …

Methylation status of VDR gene and its association with vitamin D status and VDR gene expression in pediatric tuberculosis disease

K Maruthai, S Sankar… - Immunological …, 2022 - Taylor & Francis
Deficiency in circulatory vitamin D level and vitamin D receptor DNA methylation could be
associated with weakened innate immune response and increased susceptibility to …

[HTML][HTML] TB‐LAMP (loop‐mediated isothermal amplification) for diagnosing pulmonary tuberculosis in children

LR Inbaraj, J Daniel, MKS Narayanan… - The Cochrane …, 2023 - ncbi.nlm.nih.gov
Background Tuberculosis, one of the deadliest diseases with high mortality and morbidity,
has now reversed its global decline trend with 10.6 million people affected in 2021 (WHO …

Role of ultrasound in the diagnosis of cervical tuberculous lymphadenitis in children

TZ Yu, Y Zhang, WZ Zhang, GY Yang - World Journal of Pediatrics, 2021 - Springer
Background To describe sonographic characteristics of cervical tuberculous lymphadenitis
(CTBL) in children, clinical information, and sonograms of 348 lymph nodes (LNs) from 57 …

Upfront Xpert MTB/RIF for diagnosis of pediatric TB—Does it work? Experience from India

A Kalra, D Parija, N Raizada, KS Sachdeva, R Rao… - PLoS …, 2020 - journals.plos.org
Background Diagnosis of TB in pediatric population poses several challenges. A novel
initiative was implemented in several major cities of India aimed at providing upfront access …

[HTML][HTML] New TB tools need to be affordable in the private sector: The case study of Xpert MTB/RIF

N Ponnudurai, CM Denkinger… - … of epidemiology and …, 2018 - ncbi.nlm.nih.gov
Of the estimated 10.4 million people who fell ill with tuberculosis (TB) in 2016, only 6.3
million people were detected and officially notified to national TB programmes, leaving a …