Chronic kidney disease (CKD) is defined by persistent urine abnormalities, structural
abnormalities or impaired excretory renal function suggestive of a loss of functional …

Senescence or normal physiologic aging portrays the expected age-related changes in the
kidney as compared to a disease that occurs in some but not all individuals. The …

Current criteria for the diagnosis of CKD in adults include persistent signs of kidney damage,
such as increased urine albumin-to-creatinine ratio or a GFR below the threshold of 60 …

Answering the question as to why we age is tantamount to answering the question of what is
life itself. There are countless theories as to why and how we age, but, until recently, the very …

Objective To examine clinical effectiveness and safety of apixaban 2.5 mg, dabigatran 110
mg, and rivaroxaban 15 mg compared with warfarin among patients with atrial fibrillation …

Acute kidney injury (AKI) is a common clinical state resulting from pathogenic conditions
such as ischemic and toxic insults. The pathophysiology of AKI shares common pathogenic …

Context Chronic kidney disease (CKD) is prevalent in older individuals, but the risk
implications of low estimated glomerular filtration rate (eGFR) and high albuminuria across …

Significant disparities in CKD rates and outcomes exist between black and white Americans.
Health disparities are defined as health differences that adversely affect disadvantaged …

A panel of internists and nephrologists developed this practical approach for the Kidney
Disease Outcomes Quality Initiative to guide assessment and care of chronic kidney disease …

As human life expectancy keeps increasing, ageing populations present a growing
challenge for clinical practices. Human ageing is associated with molecular, structural, and …