The uptake of calcium into and extrusion of calcium from the mitochondrial matrix is a
fundamental biological process that has critical effects on cellular metabolism, signaling …

Mitochondria sense and respond to many stressors and can support cell survival or death
through energy production and signalling pathways. Mitochondrial responses depend on …

The endoplasmic reticulum (ER) acts as a moving organelle with many important cellular
functions. As the ER lacks sufficient nutrients under pathological conditions leading to …

Both mitochondria and lysosomes are essential for maintaining cellular homeostasis, and
dysfunction of both organelles has been observed in multiple diseases,,,. Mitochondria are …

Close proximities between organelles have been described for decades. However, only
recently a specific field dealing with organelle communication at membrane contact sites …

Mitochondria are inextricably linked to the development of diseases and cell metabolism
disorders. Super-resolution imaging (SRI) is crucial in enhancing our understanding of …

Interorganellar contacts are increasingly recognized as central to the control of cellular
behavior. These contacts, which typically involve a small fraction of the endomembrane …

The NLRP3 inflammasome is a multiprotein platform which is activated upon cellular
infection or stress. Its activation leads to caspase-1-dependent secretion of proinflammatory …

Mitochondria are key determinants of cellular health. However, the functional role of
mitochondria varies from cell to cell depending on the relative demands for energy …

The endoplasmic reticulum (ER) and mitochondria cannot be considered as static structures,
as they intimately communicate, forming very dynamic platforms termed mitochondria …