Bisphosphonates are widely used as anti-resorptive agents for the treatment of various bone
and joint diseases, including advanced osteoporosis, multiple myeloma, bone metastatic …

Isoprenoids are the output of the polymerization of five-carbon, branched isoprenic chains
derived from isopentenyl pyrophosphate (IPP) and its isomer, dimethylallyl pyrophosphate …

Background: Invasive dental treatment in patients exposed to antiresorptive and
antiangiogenic drugs can cause medication-related osteonecrosis of the jaw (MRONJ) …

Medication-related osteonecrosis of the jaw (MRONJ) is a growing problem without an
effective treatment, presenting as necrotic bone sections exposed via lesions in the …

Medication-related osteonecrosis of the jaw (ONJ) is a rare but significant adverse side
effect of antiresorptive drugs. Bisphosphonate-related ONJ (BRONJ) is the most prevalent …

Objective This study was performed to determine whether the results of prevailing in vivo
and in vitro studies offer a reliable model for investigation of medication-related …

Medication-related osteonecrosis of the jaw (MRONJ) is a serious adverse effect of
antiresorptive and antiangiogenic therapies. MRONJ is identified by chronic wounds in the …

Introduction Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a serious
complication of bisphosphonate therapy. The mechanism underlying BRONJ pathogenesis …

Objective This study investigated the effects of bisphosphonates and denosumab on human
gingival fibroblasts (HGFs) that could influence inflammation, wound healing, and …

This study evaluated the effects of local application of autologous platelet-rich plasma (PRP)
on the tooth extraction site of rats presenting the main risk factors for medication-related …