Filamentous fungi are widely used in biotechnology as cell factories for the production of
chemicals, pharmaceuticals and enzymes. In order to improve their productivities, genetic …

Within five years, the CRISPR-Cas system has emerged as the dominating tool for genome
engineering, while also changing the speed and efficiency of metabolic engineering in …

Targeted gene replacement to generate knock-outs and knock-ins is a commonly used
method to study the function of unknown genes. In the methylotrophic yeast Pichia pastoris …

The opportunistic fungal pathogen Candida glabrata is a frequent cause of candidiasis,
causing infections ranging from superficial to life-threatening disseminated disease. The …

The ascomycetous yeast Yarrowia lipolytica has been established as model system for
studies of several research topics as well as for biotechnological processes in the last two …

The oleaginous yeast Yarrowia lipolytica is widely used for the production of both bulk and
fine chemicals, including organic acids, fatty acid-derived biofuels and chemicals …

The intestinal resident Candida glabrata opportunistically infects humans. However few
genetic factors for adaptation in the intestine are identified in this fungus. Here we describe …

We designed experiments to assess whether fungal cell wall mannans function as an
immune shield or an immune agonist. Fungal cell wall β-(1, 3)-glucan normally plays a …

In recent years, there has been a noticeable increase in research interests on the Fusarium
species, which includes prevalent plant pathogens and human pathogens, common …

Sterol import has been characterized under various conditions in three distinct fungal
species, the model organism Saccharomyces cerevisiae and two human fungal pathogens …