m6A modification: recent advances, anticancer targeted drug discovery and beyond

LJ Deng, WQ Deng, SR Fan, MF Chen, M Qi, WY Lyu… - Molecular cancer, 2022 - Springer
Abstract Abnormal N6-methyladenosine (m6A) modification is closely associated with the
occurrence, development, progression and prognosis of cancer, and aberrant m6A …

Review on natural products databases: where to find data in 2020

M Sorokina, C Steinbeck - Journal of cheminformatics, 2020 - Springer
Natural products (NPs) have been the centre of attention of the scientific community in the
last decencies and the interest around them continues to grow incessantly. As a …

Molecular docking study of potential phytochemicals and their effects on the complex of SARS-CoV2 spike protein and human ACE2

A Basu, A Sarkar, U Maulik - Scientific reports, 2020 - nature.com
Abstract Angiotensin converting enzyme 2 (ACE2)(EC: 3.4. 17.23) is a transmembrane
protein which is considered as a receptor for spike protein binding of novel coronavirus …

A drug-likeness toolbox facilitates ADMET study in drug discovery

CY Jia, JY Li, GF Hao, GF Yang - Drug discovery today, 2020 - Elsevier
Highlights•Online resources facilitate in silico drug-likeness study.•Databases gathering
high quality and up to date data are essential for drug-likeness evaluation.•Web servers for …

Open access in silico tools to predict the ADMET profiling of drug candidates

S Kar, J Leszczynski - Expert opinion on drug discovery, 2020 - Taylor & Francis
Introduction We are in an era of bioinformatics and cheminformatics where we can predict
data in the fields of medicine, the environment, engineering and public health. Approaches …

IMPPAT 2.0: An enhanced and expanded phytochemical atlas of Indian medicinal plants

RP Vivek-Ananth, K Mohanraj, AK Sahoo, A Samal - ACS omega, 2023 - ACS Publications
Compilation, curation, digitization, and exploration of the phytochemical space of Indian
medicinal plants can expedite ongoing efforts toward natural product and traditional …

In silico identification of potential inhibitors from Cinnamon against main protease and spike glycoprotein of SARS CoV-2

D Prasanth, M Murahari, V Chandramohan… - Journal of …, 2021 - Taylor & Francis
Cinnamon has been utilized to remedy a lot of afflictions of humans. Literary works illustrate
that it possesses numerous biological activities. Our research study is intended to recognize …

Phytochemicals as potential anticancer drugs: time to ponder nature's bounty

MA Ashraf - BioMed research international, 2020 - Wiley Online Library
Medicinal plants have been used from the beginning of human civilization, which is mostly
evident from the ancient script and traditional herbal medicine recipe. Despite the historically …

A computational prediction of SARS-CoV-2 structural protein inhibitors from Azadirachta indica (Neem)

S Borkotoky, M Banerjee - Journal of Biomolecular Structure and …, 2021 - Taylor & Francis
The rapid global spread of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-
CoV-2) has created an unprecedented healthcare crisis. The treatment for the severe …

Pharmacoinformatics-based investigation of bioactive compounds of Rasam (South Indian recipe) against human cancer

AK Kalimuthu, T Panneerselvam, P Pavadai… - Scientific reports, 2021 - nature.com
Spice-rich recipes are referred to as “functional foods” because they include a variety of
bioactive chemicals that have health-promoting properties, in addition to their nutritional …