Vanadium in biological action: chemical, pharmacological aspects, and metabolic implications in diabetes mellitus

S Treviño, A Díaz, E Sánchez-Lara… - Biological trace element …, 2019 - Springer
Vanadium compounds have been primarily investigated as potential therapeutic agents for
the treatment of various major health issues, including cancer, atherosclerosis, and …

Binding of vanadium ions and complexes to proteins and enzymes in aqueous solution

JC Pessoa, MFA Santos, I Correia, D Sanna… - Coordination Chemistry …, 2021 - Elsevier
The understanding of the role of vanadium enzymes and of vanadium compounds (VCs) in
biology, as well as the design of new vanadium-based species for catalysis, materials …

Vanadium and proteins: Uptake, transport, structure, activity and function

JC Pessoa, E Garribba, MFA Santos… - Coordination chemistry …, 2015 - Elsevier
Vanadium is an element ubiquitously present in our planet's crust and thus there are several
organisms that use vanadium for activity or function of proteins. Examples are the vanadium …

Thirty years through vanadium chemistry

JC Pessoa - Journal of Inorganic Biochemistry, 2015 - Elsevier
The relevance of vanadium in biological systems is known for many years and vanadium-
based catalysts have important industrial applications, however, till the beginning of the 80s …

Perspectives for vanadium in health issues

D Rehder - Future medicinal chemistry, 2016 - Taylor & Francis
Vanadium is omnipresent in trace amounts in the environment, in food and also in the
human body, where it might serve as a regulator for phosphate-dependent proteins …

Therapeutic potential of vanadium complexes with 1, 10-phenanthroline ligands, quo vadis? Fate of complexes in cell media and cancer cells

P Nunes, I Correia, I Cavaco, F Marques… - Journal of Inorganic …, 2021 - Elsevier
Abstract V IV O-complexes formulated as [V IV O (OSO 3)(phen) 2](1)(phen= 1, 10-
phenanthroline),[V IV O (OSO 3)(Me 2 phen) 2](2)(Me 2 phen= 4, 7-dimethyl-1, 10 …

Misinterpretations in evaluating interactions of vanadium complexes with proteins and other biological targets

JC Pessoa, I Correia - Inorganics, 2021 - mdpi.com
In aqueous media, VIV-and VV-ions and compounds undergo chemical changes such as
hydrolysis, ligand exchange and redox reactions that depend on pH and concentration of …

Copper (II) and oxidovanadium (IV) complexes of chromone Schiff bases as potential anticancer agents

P Nunes, Y Yildizhan, Z Adiguzel, F Marques… - JBIC Journal of …, 2022 - Springer
We report the synthesis, characterization and biological screening of new chromone Schiff
bases derived from the condensation of three 6-substituted-3-formyl-chromones with …

Hydrolysis, Ligand Exchange, and Redox Properties of Vanadium Compounds: Implications of Solution Transformation on Biological, Therapeutic, and Environmental …

R Dinda, E Garribba, D Sanna, DC Crans… - Chemical …, 2025 - ACS Publications
Vanadium is a transition metal with important industrial, technological, biological, and
biomedical applications widespread in the environment and in living beings. The different …

Multiple and variable binding of pharmacologically active Bis (maltolato) oxidovanadium (IV) to lysozyme

G Ferraro, M Paolillo, G Sciortino, E Garribba… - Inorganic …, 2022 - ACS Publications
The interaction with proteins of metal-based drugs plays a crucial role in their transport,
mechanism, and activity. For an active ML n complex, where L is the organic carrier, various …