Defining postpartum uterine disease and the mechanisms of infection and immunity in the female reproductive tract in cattle

IM Sheldon, J Cronin, L Goetze, G Donofrio… - Biology of …, 2009 - academic.oup.com
Uterine microbial disease affects half of all dairy cattle after parturition, causing infertility by
disrupting uterine and ovarian function. Infection with Escherichia coli, Arcanobacterium …

Galectin-1: a small protein with major functions

I Camby, M Le Mercier, F Lefranc, R Kiss - Glycobiology, 2006 - academic.oup.com
Galectins are a family of carbohydrate-binding proteins with an affinity for β-galactosides.
Galectin-1 (Gal-1) is differentially expressed by various normal and pathological tissues and …

A pivotal role for galectin-1 in fetomaternal tolerance

SM Blois, JM Ilarregui, M Tometten, M Garcia… - Nature medicine, 2007 - nature.com
A successful pregnancy requires synchronized adaptation of maternal immune-endocrine
mechanisms to the fetus. Here we show that galectin-1 (Gal-1), an immunoregulatory glycan …

Tissue-and cell-specific localization of galectins, β-galactose-binding animal lectins, and their potential functions in health and disease

J Nio-Kobayashi - Anatomical science international, 2017 - Springer
Fifteen galectins, β-galactose-binding animal lectins, are known to be distributed throughout
the body. We herein summarize current knowledge on the tissue-and cell-specific …

Galectin‐1 on cervical epithelial cells is a receptor for the sexually transmitted human parasite Trichomonas vaginalis

CYM Okumura, LG Baum, PJ Johnson - Cellular microbiology, 2008 - Wiley Online Library
The extracellular protozoan parasite Trichomonas vaginalis causes the most prevalent non‐
viral sexually transmitted human infection, yet the pathogenesis of infection is poorly …

Galectin-3 deficiency in pregnancy increases the risk of fetal growth restriction (FGR) via placental insufficiency

N Freitag, I Tirado-Gonzalez, G Barrientos… - Cell Death & …, 2020 - nature.com
Fetal growth restriction (FGR) is the most common pregnancy complication in developed
countries. Pregnancies affected by FGR, frequently concur with complications and high risk …

Involvement of galectin-1 in reproduction: past, present and future

G Barrientos, N Freitag… - Human reproduction …, 2014 - academic.oup.com
BACKGROUND After recognition of its pivotal contribution to fetomaternal tolerance, the
study of galectin-1 (gal-1) functions in the context of pregnancy became an attractive topic in …

Galectins: guardians of eutherian pregnancy at the maternal–fetal interface

NG Than, R Romero, CJ Kim, MR McGowen… - Trends in Endocrinology …, 2012 - cell.com
Galectins are multifunctional regulators of fundamental cellular processes. They are also
involved in innate and adaptive immune responses, and play a functional role in immune …

Pregnancy galectinology: insights into a complex network of glycan binding proteins

SM Blois, G Dveksler, GR Vasta, N Freitag… - Frontiers in …, 2019 - frontiersin.org
Galectins are a phylogenetically conserved family of soluble β-galactoside binding proteins,
consisting of 15 different types, each with a specific function. Galectins contribute to …

Expression of galectin-1,-3 (gal-1, gal-3) and the Thomsen–Friedenreich (TF) antigen in normal, IUGR, preeclamptic and HELLP placentas

U Jeschke, D Mayr, B Schiessl, I Mylonas, S Schulze… - Placenta, 2007 - Elsevier
BACKGROUND: Galectin-1 (gal-1) and galectin-3 (gal-3), which are members of the
mammalian β-galactoside-binding proteins, recognise preferentially (Galβ1-4GlcNAc) …