[HTML][HTML] Fungal iron homeostasis with a focus on Aspergillus fumigatus

M Misslinger, P Hortschansky, AA Brakhage… - Biochimica et Biophysica …, 2021 - Elsevier
To maintain iron homeostasis, fungi have to balance iron acquisition, storage, and utilization
to ensure sufficient supply and to avoid toxic excess of this essential trace element. As …

Exploring cuproptosis as a mechanism and potential intervention target in cardiovascular diseases

Y Yang, Q Feng, Y Luan, H Liu, Y Jiao, H Hao… - Frontiers in …, 2023 - frontiersin.org
Copper (Cu) is a vital trace element for maintaining human health. Current evidence
suggests that genes responsible for regulating copper influx and detoxification help …

[HTML][HTML] An update on ABC transporters of filamentous fungi–from physiological substrates to xenobiotics

J Víglaš, P Olejníková - Microbiological Research, 2021 - Elsevier
The superfamily of ATP-binding cassette (ABC) transporters is a large family of proteins with
a wide substrate repertoire and range of functions. The main role of these proteins is in the …

Iron–sulfur cluster signaling: The common thread in fungal iron regulation

M Gupta, CE Outten - Current opinion in chemical biology, 2020 - Elsevier
Iron homeostasis in fungi involves balancing iron uptake and storage with iron utilization to
achieve adequate, nontoxic levels of this essential nutrient. Extensive work in the …

Multiple roles of ABC transporters in yeast

S Kumari, M Kumar, NA Gaur, R Prasad - Fungal Genetics and Biology, 2021 - Elsevier
The ATP binding cassette (ABC) transporters, first discovered as high-affinity nutrient
importers in bacteria, rose to prominence when their ability to confer multidrug resistance …

Respiring to infect: Emerging links between mitochondria, the electron transport chain, and fungal pathogenesis

B Black, C Lee, LC Horianopoulos, WH Jung… - PLoS …, 2021 - journals.plos.org
Fungal pathogens threaten human health both directly as infectious agents and indirectly by
limiting crop production, and new approaches are desperately needed to combat fungal …

Membrane disruption of Fusarium oxysporum f. sp. niveum induced by myriocin from Bacillus amyloliquefaciens LZN01

H Wang, Z Wang, Z Liu, K Wang… - Microbial …, 2021 - Wiley Online Library
Myriocin, which is produced by Bacillus amyloliquefaciens LZN01, can inhibit the growth of
Fusarium oxysporum f. sp. niveum (Fon). In the present study, the antifungal mechanism of …

A fungal ABC transporter FgAtm1 regulates iron homeostasis via the transcription factor cascade FgAreA-HapX

Z Wang, T Ma, Y Huang, J Wang, Y Chen… - PLoS …, 2019 - journals.plos.org
Iron homeostasis is important for growth, reproduction and other metabolic processes in all
eukaryotes. However, the functions of ATP-binding cassette (ABC) transporters in iron …

Genomic Multiplication and Drug Efflux Influence Ketoconazole Resistance in Malassezia restricta

M Park, YJ Cho, YW Lee, WH Jung - Frontiers in cellular and infection …, 2020 - frontiersin.org
Malassezia restricta is an opportunistic fungal pathogen on human skin; it is associated with
various skin diseases, including seborrheic dermatitis and dandruff, which are usually …

Iron-sensing is governed by mitochondrial, not by cytosolic iron–sulfur cluster biogenesis in Aspergillus fumigatus

M Misslinger, BE Lechner, K Bacher, H Haas - Metallomics, 2018 - academic.oup.com
Microorganisms have to adapt their metabolism to the requirements of their ecological niche
to avoid iron shortage as well as iron toxicity. Therefore, mechanisms have been evolved to …