B. Kidney C. Other tissues D. Extracellular insulin degradation III. Cellular Insulin Uptake IV.
Cellular Insulin Degradation A. Degradation products B. Assay for insulin degradation C …

Asymmetric cell division, which includes cell polarization and cytokinesis, is essential for
generating cell diversity during development. The budding yeast Saccharomyces cerevisiae …

The Saccharomyces cerevisiae BNI1 gene product (Bni1p) is a member of the formin family
of proteins, which participate in cell polarization, cytokinesis, and vertebrate limb formation …

The establishment of cell polarity is critical for the development of many organisms and for
the function of many cell types. A large number of studies of diverse organisms from yeast to …

Abstract Insulin-degrading enzyme (IDE), a Zn2+-metalloprotease, is involved in the
clearance of insulin and amyloid-β (refs). Loss-of-function mutations of IDE in rodents cause …

The malaria parasite Plasmodium falciparum degrades hemoglobin in its acidic food
vacuole for use as a major nutrient source. A novel metallopeptidase activity, falcilysin, was …

Cell division facilitated by a contractile ring is an almost universal feature across all
branches of cellular life, with the notable exception of higher plants. In all organisms that use …

▪ Abstract Eukaryotic cells respond to intracellular and extracellular cues to direct
asymmetric cell growth and division. The yeast Saccharomyces cerevisiae undergoes …

Insulin-degrading enzyme (IDE) is a highly conserved and ubiquitously expressed
metalloprotease that degrades insulin and several other intermediate-size peptides. For …

Prelamin A undergoes multistep processing to yield lamin A, a structural protein of the
nuclear lamina. Prelamin A terminates with a CAAX motif, which triggers farnesylation of a C …